In the dynamic field of chemical synthesis, the availability of versatile and high-quality building blocks is crucial for innovation. 3-Bromo-5-fluoropyridine-2-carbonitrile (CAS: 950670-18-5) stands out as a particularly important heterocyclic intermediate, enabling the construction of complex molecules for various high-value applications. This article delves into its chemical significance and the advantages of securing this compound from a trusted manufacturer.

Chemical Properties and Reactivity

With the molecular formula C6H2BrFN2 and a molecular weight of 201.00, 3-Bromo-5-fluoropyridine-2-carbonitrile is a pyridine derivative featuring strategic functional groups. The bromine atom is a well-known leaving group, facilitating palladium-catalyzed cross-coupling reactions like Suzuki, Stille, or Buchwald-Hartwig aminations. The nitrile group can be hydrolyzed to a carboxylic acid, reduced to an amine, or used in cycloaddition reactions. The fluorine atom can influence electron density, lipophilicity, and metabolic stability in derived compounds. This trifecta of reactivity makes it an exceptionally valuable synthon for chemists.

Applications Across Industries

The versatility of 3-Bromo-5-fluoropyridine-2-carbonitrile translates into significant applications in several key industries:

  • Pharmaceuticals: As a core component in drug discovery, it's used to synthesize novel drug candidates targeting a wide array of diseases. Researchers actively search for 'pharmaceutical intermediates' that offer unique structural motifs, and this pyridine derivative fits that description perfectly. By using it, scientists can efficiently build complex molecular scaffolds for potential APIs.
  • Agrochemicals: The development of next-generation pesticides, herbicides, and fungicides often relies on sophisticated chemical structures. 3-Bromo-5-fluoropyridine-2-carbonitrile serves as a critical intermediate in creating compounds with enhanced efficacy and selectivity.
  • Materials Science: While less common, heterocyclic compounds can also find applications in advanced materials, such as organic electronics or specialized polymers.

Securing Your Supply Chain

For businesses looking to buy 3-Bromo-5-fluoropyridine-2-carbonitrile, selecting the right supplier is paramount. A reputable manufacturer in China, like NINGBO INNO PHARMCHEM CO.,LTD., offers not only competitive pricing but also assurance of quality and consistent availability. When evaluating potential suppliers, consider factors such as purity specifications, adherence to regulatory standards, and the responsiveness of their sales and technical teams. It's often beneficial to request a sample for initial testing and to inquire about bulk purchase options if your needs scale up.

In summary, 3-Bromo-5-fluoropyridine-2-carbonitrile is more than just a chemical compound; it's a gateway to innovation in synthesis. Ensuring a reliable supply from a trustworthy manufacturer allows researchers and production managers to push the boundaries of what's possible in chemical development.