The Role of 4-Bromobutyl Acetate in Pharmaceutical Synthesis
The pharmaceutical industry relies heavily on a robust supply of high-quality chemical intermediates to synthesize life-saving drugs. Among these crucial compounds is 4-Bromobutyl Acetate (CAS 4753-59-7), a versatile building block that plays a significant role in the creation of various Active Pharmaceutical Ingredients (APIs). For pharmaceutical R&D scientists and procurement managers, understanding its properties and sourcing reliable supply is paramount.
4-Bromobutyl Acetate, characterized by its molecular formula C6H11BrO2, is an ester that contains a primary alkyl bromide functional group. This combination makes it an excellent precursor for introducing butyl acetate moieties into target molecules or for further functionalization via nucleophilic substitution at the bromide site. Its common appearance as a colorless to light yellow liquid, with a typical assay of 97%min, is well-documented by reputable manufacturers.
In pharmaceutical synthesis, intermediates like 4-Bromobutyl Acetate are used in multi-step reaction sequences to build complex molecular structures. The quality of these intermediates directly influences the yield, purity, and overall success of the API synthesis. Therefore, pharmaceutical companies must source their 4-Bromobutyl Acetate from manufacturers who adhere to strict quality control measures and international standards, such as USP, BP, or EP, where applicable, even for intermediates.
When looking to buy 4-Bromobutyl Acetate for pharmaceutical applications, it is essential to partner with suppliers who can provide comprehensive documentation, including detailed Certificates of Analysis (CoA) for each batch. These CoAs should clearly outline the purity assay, impurity profiles, and confirmation of compliance with any specified standards. This meticulous approach ensures that the procured material is suitable for its intended pharmaceutical use and minimizes risks associated with synthesis variability.
Procurement managers often face the challenge of balancing cost with quality. China manufacturers, like the one featured, often provide a competitive price for 4-Bromobutyl Acetate, making it an attractive option for cost-conscious drug development. However, it is crucial to select suppliers who demonstrate a strong commitment to quality assurance and regulatory compliance, ensuring that the price advantage does not compromise the integrity of the final pharmaceutical product.
In summary, 4-Bromobutyl Acetate is a cornerstone intermediate in many pharmaceutical synthesis pathways. For optimal results and regulatory adherence, it is imperative for buyers to prioritize sourcing from reliable manufacturers who guarantee high purity and provide robust quality documentation. Engaging with experienced suppliers ensures a consistent and dependable supply for critical drug development projects.
Perspectives & Insights
Nano Explorer 01
“Its common appearance as a colorless to light yellow liquid, with a typical assay of 97%min, is well-documented by reputable manufacturers.”
Data Catalyst One
“In pharmaceutical synthesis, intermediates like 4-Bromobutyl Acetate are used in multi-step reaction sequences to build complex molecular structures.”
Chem Thinker Labs
“The quality of these intermediates directly influences the yield, purity, and overall success of the API synthesis.”