In the intricate world of chemical synthesis, certain molecules stand out for their utility and versatility. 7-Nitroquinazolin-4(3H)-one, identified by its CAS number 20872-93-9, is one such compound. This heterocyclic organic molecule, characterized by its nitro group and quinazolinone core, has carved a significant niche as a foundational building block in various research and industrial applications. Understanding its properties and synthetic roles is key for chemists seeking to innovate.

Chemical Identity and Properties

7-Nitroquinazolin-4(3H)-one boasts the molecular formula C8H5N3O3 and a molecular weight of 191.14 g/mol. Typically appearing as a light yellow to brown solid, its purity, often specified at over 98%, is a critical factor for its effective use. The quinazolinone scaffold itself is a prevalent structure in medicinal chemistry, known for its diverse biological activities. The presence of the nitro group at the 7-position further influences its reactivity and electronic properties, making it a valuable intermediate for further chemical modifications.

Applications in Organic Synthesis and Drug Discovery

The primary utility of 7-Nitroquinazolin-4(3H)-one lies in its role as an intermediate in the synthesis of more complex molecules. Its structure allows for various chemical transformations, including reduction of the nitro group to an amine, or modifications to the quinazolinone ring system. This makes it particularly valuable in:

  • Pharmaceutical Intermediate Synthesis: Researchers frequently employ this compound in the development of novel drug candidates. The quinazolinone core is found in many bioactive molecules, including anticancer agents, antihypertensives, and anti-inflammatory drugs. The nitro group can be converted into an amine, which is a common functional group for further derivatization in medicinal chemistry.
  • Agrochemical Development: Similar to pharmaceuticals, agrochemicals often utilize complex heterocyclic structures. 7-Nitroquinazolin-4(3H)-one can serve as a precursor for new pesticides or plant growth regulators.
  • Material Science: The electronic properties imparted by the nitro group and the heterocyclic nature of the molecule may lend themselves to applications in material science, such as in the development of organic electronic materials or specialized dyes.

Procurement and Reliability for Research

For laboratories and research institutions, obtaining 7-Nitroquinazolin-4(3H)-one from reliable manufacturers is crucial. When you search to buy this compound, prioritize suppliers who guarantee high purity and provide comprehensive technical data. Companies that specialize in building blocks and intermediates, often based in key chemical manufacturing regions like China, are frequently excellent sources. Engaging with a supplier that offers both research-grade quantities and potential for bulk manufacturing ensures a smooth transition from lab-scale experimentation to larger-scale production if your project demands it. Always check for clear product specifications and inquire about pricing for your required quantities.

In essence, 7-Nitroquinazolin-4(3H)-one is more than just a chemical; it's a gateway to innovation. Its strategic placement within synthetic routes makes it an indispensable tool for chemists pushing the boundaries of drug discovery and organic synthesis. By partnering with reputable suppliers, researchers can ensure the quality and availability needed to bring their groundbreaking ideas to fruition.