The pharmaceutical industry constantly seeks innovative molecules with enhanced efficacy and improved pharmacokinetic profiles. Fluorinated compounds have played an increasingly significant role in achieving these goals, and 1,2,3,4-Tetrafluorobenzene (CAS 551-62-2) is a prime example of a versatile building block in this domain. For research scientists and pharmaceutical chemists, understanding its utility and sourcing it reliably is a critical aspect of the drug development pipeline.

Fluorine's Impact on Drug Properties

The strategic introduction of fluorine atoms into organic molecules can profoundly alter their properties. Fluorine's high electronegativity and small atomic radius can influence a molecule's metabolic stability, lipophilicity, binding affinity to target receptors, and even its pKa. These effects are highly desirable for creating drugs that are more potent, have a longer duration of action, and exhibit better absorption and distribution within the body. 1,2,3,4-Tetrafluorobenzene, with its tetra-substituted aromatic ring, offers a readily available source of fluorinated benzene moiety for complex syntheses.

1,2,3,4-Tetrafluorobenzene as a Pharmaceutical Intermediate

As a chemical intermediate, 1,2,3,4-Tetrafluorobenzene serves as a precursor for a wide array of fluorinated active pharmaceutical ingredients (APIs). Its specific substitution pattern allows for regioselective reactions, enabling chemists to build complex molecular architectures. Researchers frequently look to buy CAS 551-62-2 when designing novel therapeutic agents targeting various diseases. The availability of this compound with high purity (typically 99%) from a trusted manufacturer is crucial, as impurities can lead to the formation of unwanted byproducts or affect the efficacy and safety of the final drug substance.

Sourcing Strategy: Prioritizing Quality and Reliability

When procuring pharmaceutical intermediates, the emphasis on quality cannot be overstated. For procurement managers, identifying a chemical intermediate supplier in China that specializes in fluorinated compounds like 1,2,3,4-Tetrafluorobenzene is key. A reputable supplier will provide:

  • Guaranteed High Purity: Ensuring the 99% purity standard is met through stringent quality control.
  • Comprehensive Documentation: Including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS).
  • Consistent Supply: Demonstrating a robust production capacity and reliable logistics.
  • Technical Support: Offering insights into product handling and application suitability.

Inquire about the price for 1,2,3,4-Tetrafluorobenzene from established manufacturers to secure a cost-effective yet high-quality supply for your critical projects.

The Future of Fluorinated Pharmaceuticals

The demand for fluorinated pharmaceuticals continues to grow, driven by their proven benefits in therapeutic outcomes. Compounds like 1,2,3,4-Tetrafluorobenzene will remain vital components in the chemist's toolkit. By establishing strong relationships with reliable suppliers of essential intermediates, pharmaceutical companies can accelerate their research and development efforts, bringing life-saving medications to market faster.

For your pharmaceutical synthesis needs, consider partnering with us for a consistent and high-quality supply of 1,2,3,4-Tetrafluorobenzene. Contact us to receive a detailed quote and learn more about our product offerings.