The intricate world of pharmaceutical development relies heavily on the availability of precise and high-quality chemical building blocks. Among these, heterocyclic compounds play a pivotal role, and 3-Bromo-1-benzothiophene (CAS 7342-82-7) stands out as a valuable intermediate. Its unique structural features make it an indispensable component in the synthesis of a wide array of pharmaceutical intermediates, ultimately contributing to the discovery and production of new therapeutic agents.

Understanding the Structure and Properties

3-Bromo-1-benzothiophene is characterized by its benzothiophene core, a bicyclic structure comprising a benzene ring fused to a thiophene ring, with a bromine atom substituted at the 3-position. This bromine atom is crucial, as it provides a reactive site for various chemical transformations, such as Suzuki-Miyaura coupling reactions, nucleophilic substitutions, and other cross-coupling chemistries. With a molecular formula of C8H5BrS and a molecular weight of 213.09, it typically presents as a liquid, ranging in color from colorless to yellow to red, with a purity often specified at 97% minimum. These properties are critical for its effective use in complex synthetic pathways.

3-Bromo-1-benzothiophene as a Pharmaceutical Intermediate

The significance of 3-Bromo-1-benzothiophene in the pharmaceutical industry stems from its ability to be readily functionalized. It acts as a scaffold upon which more complex molecular structures can be built. Researchers often seek to buy 3-Bromo-1-benzothiophene because it allows for the introduction of various pharmacologically active groups. For instance, derivatives of benzothiophene have demonstrated a broad spectrum of biological activities, including antimicrobial, anti-inflammatory, anticancer, and antiviral properties. This makes 3-Bromo-1-benzothiophene a critical starting material for synthesizing novel drug candidates aimed at treating a wide range of diseases.

When pharmaceutical companies or contract research organizations (CROs) are looking to purchase 3-Bromo-1-benzothiophene, they require assurance of quality and consistent availability. A reliable manufacturer of 3-Bromo-1-benzothiophene in China can provide the necessary purity and volume to support both early-stage research and later-stage clinical development. The competitive price of 3-Bromo-1-benzothiophene from these suppliers further aids in managing the extensive costs associated with drug discovery.

Sourcing for Pharmaceutical Applications

For those involved in pharmaceutical R&D, selecting the right 3-Bromo-1-benzothiophene supplier is as important as the synthesis itself. Key considerations include:

  • Purity: Pharmaceutical applications demand exceptionally high purity to avoid side reactions and ensure the efficacy and safety of the final drug product.
  • Scalability: The ability to transition from gram-scale research quantities to kilogram or ton-scale production is vital as a drug candidate progresses through clinical trials.
  • Regulatory Compliance: While 3-Bromo-1-benzothiophene is an intermediate, suppliers familiar with pharmaceutical industry standards can provide necessary documentation.
  • Reliability: A consistent supply chain is crucial to prevent disruptions in research timelines and manufacturing schedules.

We are a dedicated chemical supplier specializing in intermediates like 3-Bromo-1-benzothiophene (CAS 7342-82-7). Our commitment to quality, competitive pricing, and reliable supply makes us an ideal partner for your pharmaceutical research and development needs. If you are seeking to source this essential intermediate, we encourage you to contact us for a quote and to learn more about our capabilities as a leading 3-Bromo-1-benzothiophene manufacturer.

By partnering with us, you ensure access to a critical building block that fuels pharmaceutical innovation, helping to bring life-saving and life-improving medications to market.