In the intricate world of pharmaceutical development, the precise selection of chemical intermediates is paramount. Among these essential building blocks, Azepane stands out as a valuable cyclic secondary amine, playing a crucial role in the synthesis of various therapeutic agents. This article delves into the significance of Azepane, its chemical properties, and its indispensable application in the production of critical pharmaceuticals, such as Bazedoxifene.

Azepane, also known by its IUPAC name Azepane or synonyms like Hexahydroazepine and Hexamethyleneamine, is a colorless to light yellow liquid with the CAS number 111-49-9. Its molecular formula C6H13N and molar mass of 99.17 g/mol define its fundamental chemical identity. The compound exhibits a relatively low melting point of -37°C and a boiling point of 142.7°C at atmospheric pressure, making it manageable under standard laboratory and industrial conditions. With a purity of ≥98.0%, it is an ideal candidate for sophisticated synthetic routes where high quality is non-negotiable.

One of the most prominent applications of Azepane lies in its role as a key intermediate in the synthesis of Bazedoxifene. Bazedoxifene is a selective estrogen receptor modulator (SERM) used in the treatment and prevention of osteoporosis in postmenopausal women. The azepane ring system provides a critical structural scaffold that contributes to the pharmacological activity of Bazedoxifene. The demand for such intermediates underscores the importance of reliable suppliers who can consistently provide high-quality Azepane to the pharmaceutical industry. For procurement managers and R&D scientists seeking to buy Azepane for such applications, sourcing from a reputable manufacturer in China can offer significant advantages in terms of cost-effectiveness and supply chain reliability.

Beyond its use in Bazedoxifene, Azepane serves as a versatile building block in broader organic synthesis. Its cyclic secondary amine structure allows for a wide range of chemical transformations, enabling the creation of novel heterocyclic compounds and more complex molecules. This adaptability makes it an attractive raw material for researchers exploring new drug candidates or developing advanced materials. When considering the purchase of Azepane, understanding its chemical properties and potential applications is key to optimizing its use in your specific project. The availability of Azepane for sale from experienced suppliers ensures that research and development pipelines can proceed without interruption.

For businesses looking to procure Azepane, partnering with an experienced manufacturer in China can provide access to competitive pricing and efficient delivery. Packaging options typically include 200 kg drums, but custom packaging can often be arranged to meet specific order requirements. Whether you are a procurement specialist looking for the best Azepane price or a research scientist needing a reliable source for Hexahydroazepine, exploring options from established chemical suppliers is a strategic move. The accessibility of this essential chemical intermediate facilitates innovation and production across the pharmaceutical and fine chemical sectors.

In conclusion, Azepane (CAS 111-49-9) is a vital chemical intermediate with significant applications, particularly in the pharmaceutical industry for the synthesis of drugs like Bazedoxifene. Its desirable chemical properties and availability from reliable manufacturers make it a cornerstone for advanced chemical synthesis. By understanding its role and sourcing effectively, companies can ensure the continued progress of their drug development and chemical manufacturing endeavors.