The Role of Diethyl 2-fluoropropanedioate in Modern Synthesis
In the dynamic world of chemical synthesis, specific molecular structures unlock pathways to groundbreaking innovations. Fluorinated organic compounds have garnered significant attention due to the unique properties fluorine imparts, such as altered electronic effects, increased lipophilicity, and enhanced metabolic stability. Among these, Diethyl 2-fluoropropanedioate emerges as a particularly valuable synthesis intermediate, serving as a cornerstone for advanced R&D in sectors like pharmaceuticals and agrochemicals.
Diethyl 2-fluoropropanedioate, identified by its chemical formula C7H11FO4 and a molecular weight of 178.158, presents itself as a clear, colorless to light yellow liquid. Its physical properties, including a density of 1.129 g/mL and a boiling point of 121-122 °C at 30 mm Hg, make it amenable to various reaction conditions. This compound is a derivative of malonic ester, a well-established class of reagents in organic synthesis, but the presence of the fluorine atom at the alpha-carbon position introduces unique reactivity and steric effects.
The primary utility of Diethyl 2-fluoropropanedioate lies in its role as a building block for more complex fluorinated molecules. In pharmaceutical synthesis, it is employed to introduce fluorinated moieties into drug candidates. This often leads to improved therapeutic indices, enhanced bioavailability, and longer half-lives for the active pharmaceutical ingredients (APIs). Researchers actively seeking to buy such intermediates can rely on manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. to supply high-purity Diethyl 2-fluoropropanedioate, ensuring the integrity of their synthesis projects.
Beyond pharmaceuticals, the agrochemical industry utilizes this compound extensively in the development of new crop protection agents. Fluorine substitution can enhance the efficacy and selectivity of herbicides, insecticides, and fungicides, leading to more targeted pest control and reduced environmental impact. For agrochemical R&D teams, identifying a dependable supplier of Diethyl 2-fluoropropanedioate is crucial for advancing their product pipelines. As a committed manufacturer in China, we understand these needs and strive to provide consistent quality and reliable delivery.
The development of a comprehensive fluorochemical platform, as pursued by NINGBO INNO PHARMCHEM CO.,LTD., is vital for supporting these advanced applications. From sourcing raw materials to mastering fluorination technologies and ensuring rigorous quality control, our aim is to be a one-stop provider. Whether you are a research scientist or a procurement specialist looking to purchase Diethyl 2-fluoropropanedioate, engaging with a direct manufacturer like us ensures you receive a product that meets your exacting standards, facilitating your groundbreaking research and development efforts.
Perspectives & Insights
Bio Analyst 88
“Fluorinated organic compounds have garnered significant attention due to the unique properties fluorine imparts, such as altered electronic effects, increased lipophilicity, and enhanced metabolic stability.”
Nano Seeker Pro
“Among these, Diethyl 2-fluoropropanedioate emerges as a particularly valuable synthesis intermediate, serving as a cornerstone for advanced R&D in sectors like pharmaceuticals and agrochemicals.”
Data Reader 7
“Diethyl 2-fluoropropanedioate, identified by its chemical formula C7H11FO4 and a molecular weight of 178.”