Quantitative Nuclear Magnetic Resonance (qNMR) has emerged as a powerful tool for accurate chemical compound analysis, offering direct, non-destructive quantification without the need for identical reference standards. For R&D scientists and laboratory managers, selecting the right internal standard is critical for the success of qNMR experiments. Among the various options, Potassium Hydrogen Phthalate (CAS 877-24-7) has gained significant traction due to its unique combination of properties. As a dedicated chemical supplier, we aim to illuminate its advantages and guide you on procuring this vital reagent.

The efficacy of qNMR relies heavily on the internal standard's stability, purity, and predictable spectroscopic behavior. Potassium Hydrogen Phthalate, often referred to as KHP, meets these criteria exceptionally well. Its well-defined structure, high purity (often exceeding 99.8%), and chemical inertness make it an ideal candidate. When you buy Potassium Hydrogen Phthalate for qNMR, you are investing in a material that provides a stable signal with minimal interference from the analyte or the solvent. Its protons give rise to characteristic signals in the ¹H NMR spectrum, typically in the 7-8 ppm region, which are usually well-resolved from most common organic molecules.

For laboratory procurement professionals, sourcing KHP requires attention to detail. The assay value is paramount, as any impurity can affect the accuracy of quantification. Furthermore, the physical form – typically a white crystalline powder – should be consistent, indicating proper manufacturing and handling. Companies that manufacture and supply chemicals like KHP must provide comprehensive Certificates of Analysis detailing purity, moisture content, and other critical parameters. This documentation is indispensable for validating the standard's suitability for qNMR applications.

The advantages of using KHP as an internal standard in qNMR are manifold. It allows for absolute quantification of an unknown analyte by comparing its integrated signal area to that of a precisely known amount of KHP. This is particularly useful when authentic reference standards for the analyte are unavailable or prohibitively expensive. Moreover, KHP’s relatively low solubility in some organic solvents can be managed by careful solvent selection or by working with KHP in its slightly more soluble forms if necessary, although its use in deuterated water for certain NMR experiments is also common.

If your research demands precise quantification via qNMR, ensuring a reliable supply of high-quality Potassium Hydrogen Phthalate is essential. As a manufacturer committed to excellence, we offer KHP that meets the stringent requirements for qNMR applications. We understand the importance of consistent quality and competitive pricing for your laboratory operations. To purchase Potassium Hydrogen Phthalate and enhance your qNMR capabilities, please contact our sales department. Let us be your trusted partner in providing the critical chemical components for your advanced analytical needs.