The Crucial Role of Propargylaldehyde Diethyl Acetal in Modern Organic Synthesis
Propargylaldehyde Diethyl Acetal, identified by its CAS number 10160-87-9, stands as a cornerstone in contemporary organic synthesis. This versatile chemical compound, often referred to by its synonyms such as 3,3-Diethoxyprop-1-yne or Propiolaldehyde Diethyl Acetal, is a critical intermediate leveraged by chemists worldwide. Its unique molecular structure, featuring both a terminal alkyne and an acetal group, endows it with exceptional reactivity and utility in constructing complex organic molecules. Ningbo Inno Pharmchem Co., Ltd. recognizes its significance as a key component for pharmaceutical intermediates and fine chemical manufacturing.
The compound's physical properties are noteworthy: it typically presents as a colorless to light yellow liquid, with a boiling point around 138-139.5°C and a density of 0.894 g/mL at 25°C. Its purity, often exceeding 97.0% by GC, makes it highly reliable for precise chemical reactions. These characteristics are vital for its primary application as a bifunctional three-carbon building block. It plays an integral role in synthesizing conjugated diynes, enynes, and dienes, which are essential precursors for a myriad of advanced materials and pharmaceuticals.
The utility of Propargylaldehyde Diethyl Acetal extends to sophisticated synthetic methodologies. For instance, it is employed in the synthesis of 3-boronoacrolein pinacolate and (E)-3-(tributylstannyl)-2-propenal, showcasing its adaptability in stereoselective reactions. Furthermore, its participation in three-component syntheses of 3-(hetero)aryl-1H-pyrazoles highlights its capacity to form heterocyclic compounds, which are prevalent in medicinal chemistry.
Ningbo Inno Pharmchem Co., Ltd. is dedicated to supplying high-quality Propargylaldehyde Diethyl Acetal, understanding its demand in sectors like pharmaceuticals, agrochemicals, and advanced materials. As industries continue to innovate, the need for reliable and versatile chemical building blocks such as this one will only grow. By providing this essential intermediate, we aim to support the groundbreaking research and manufacturing efforts of our clients, reinforcing our commitment to advancing chemical synthesis and product development.
The compound's physical properties are noteworthy: it typically presents as a colorless to light yellow liquid, with a boiling point around 138-139.5°C and a density of 0.894 g/mL at 25°C. Its purity, often exceeding 97.0% by GC, makes it highly reliable for precise chemical reactions. These characteristics are vital for its primary application as a bifunctional three-carbon building block. It plays an integral role in synthesizing conjugated diynes, enynes, and dienes, which are essential precursors for a myriad of advanced materials and pharmaceuticals.
The utility of Propargylaldehyde Diethyl Acetal extends to sophisticated synthetic methodologies. For instance, it is employed in the synthesis of 3-boronoacrolein pinacolate and (E)-3-(tributylstannyl)-2-propenal, showcasing its adaptability in stereoselective reactions. Furthermore, its participation in three-component syntheses of 3-(hetero)aryl-1H-pyrazoles highlights its capacity to form heterocyclic compounds, which are prevalent in medicinal chemistry.
Ningbo Inno Pharmchem Co., Ltd. is dedicated to supplying high-quality Propargylaldehyde Diethyl Acetal, understanding its demand in sectors like pharmaceuticals, agrochemicals, and advanced materials. As industries continue to innovate, the need for reliable and versatile chemical building blocks such as this one will only grow. By providing this essential intermediate, we aim to support the groundbreaking research and manufacturing efforts of our clients, reinforcing our commitment to advancing chemical synthesis and product development.
Perspectives & Insights
Logic Thinker AI
“This versatile chemical compound, often referred to by its synonyms such as 3,3-Diethoxyprop-1-yne or Propiolaldehyde Diethyl Acetal, is a critical intermediate leveraged by chemists worldwide.”
Molecule Spark 2025
“Its unique molecular structure, featuring both a terminal alkyne and an acetal group, endows it with exceptional reactivity and utility in constructing complex organic molecules.”
Alpha Pioneer 01
“recognizes its significance as a key component for pharmaceutical intermediates and fine chemical manufacturing.”