The development of effective veterinary pharmaceuticals relies on the consistent supply of high-quality chemical intermediates. Among these, Toltrazuril (CAS 69004-03-1) holds a significant position as a crucial component in the formulation of anticoccidial drugs. Its specific chemical structure and potent biological activity make it indispensable for combating parasitic diseases like coccidiosis in livestock and poultry. This article delves into Toltrazuril's role as a chemical intermediate and the importance of its procurement from reliable sources.

Toltrazuril: Chemical Profile and Significance

Toltrazuril, with the molecular formula C18H14F3N3O4S, is a synthetic triazinetrione derivative. Its chemical properties, including its solubility in organic solvents and relative stability, make it suitable for various formulation processes. As a pharmaceutical intermediate, its primary function is to serve as the active pharmaceutical ingredient (API) in anticoccidial medications. The purity and quality of this intermediate directly dictate the efficacy and safety of the final veterinary drug.

Mechanism of Action and Application as an Intermediate

Toltrazuril's powerful anticoccidial activity stems from its ability to interfere with the intracellular development of Eimeria parasites. It targets key biological processes within the protozoa, leading to their destruction. As a chemical intermediate, it is typically synthesized through complex chemical pathways and then purified to meet stringent pharmaceutical standards. Manufacturers that specialize in producing Toltrazuril powder ensure that it is in a form that can be easily incorporated into oral suspensions, feed premixes, or other delivery systems commonly used in veterinary medicine.

Importance of Sourcing from Qualified Manufacturers

When considering where to buy Toltrazuril, the choice of supplier is critical. Pharmaceutical companies and veterinary drug manufacturers must partner with chemical suppliers who can guarantee high purity levels (often exceeding 99%) and consistent quality. Reputable manufacturers, particularly those based in China, have developed expertise in the synthesis and purification of complex chemical intermediates like Toltrazuril. They often operate under strict quality control systems, such as ISO certifications, ensuring that their products meet global pharmaceutical standards.

Procurement Considerations for Toltrazuril

  • Purity Assurance: Verify that the supplier provides a Certificate of Analysis (CoA) confirming the purity and specifications of the Toltrazuril.
  • Manufacturing Scale and Capacity: Ensure the manufacturer can meet your required production volumes consistently.
  • Competitive Toltrazuril Price: Obtaining competitive pricing is crucial for cost-effective drug development. Direct sourcing from manufacturers often yields better value.
  • Regulatory Support: A qualified supplier can provide necessary documentation and support for regulatory submissions.

In conclusion, Toltrazuril (CAS 69004-03-1) is more than just a drug; it is a vital chemical intermediate whose quality directly influences the effectiveness of veterinary medicines. Sourcing this essential compound from trustworthy manufacturers, particularly those with established production capabilities in China, ensures the integrity and success of veterinary pharmaceutical products aimed at safeguarding animal health worldwide.