When working with chemical compounds, a thorough understanding of their properties, potential hazards, and safe handling procedures is non-negotiable. 3-Ethynylpyridine (CAS 2510-23-8), a valuable intermediate in organic synthesis, is no exception. As a responsible chemical supplier, providing clear information on its safety profile is a key part of our service to researchers and industrial users. This article outlines the critical safety aspects of 3-Ethynylpyridine, ensuring its use is both effective and secure.

Key Properties and Hazard Identification

3-Ethynylpyridine is typically encountered as a white solid with a melting point around 39-40°C. While specific odour data may vary, its primary classification highlights it as a flammable solid. According to GHS classifications found in Safety Data Sheets (SDS), it can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). The flammable nature (H228) requires careful attention to ignition sources.

The signal word for 3-Ethynylpyridine is 'Danger', indicating the need for significant caution. Precautionary statements emphasize preventing exposure and managing risks:

  • P210: Keep away from heat, sparks, open flames, and hot surfaces. No smoking.
  • P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280: Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

These classifications are essential for anyone looking to buy 3-Ethynylpyridine and incorporate it into their workflows.

Safe Handling and Storage Practices

To mitigate the risks associated with 3-Ethynylpyridine, meticulous handling and storage are crucial:

  • Ventilation: Always handle the compound in a well-ventilated area, preferably under a fume hood, to avoid inhalation of dust or vapours.
  • Personal Protective Equipment (PPE): Essential PPE includes safety glasses with side-shields, chemically resistant gloves (e.g., nitrile), and protective clothing. Ensure gloves are inspected before use and removed properly to avoid skin contact.
  • Ignition Sources: Due to its flammability, keep 3-Ethynylpyridine away from all potential ignition sources. Use non-sparking tools and ensure electrical equipment is explosion-proof.
  • Storage: Store containers tightly closed in a dry, cool, and well-ventilated place. Protect from heat and direct sunlight. Ensure proper grounding of containers to prevent static discharge.

Emergency Procedures and Disposal

In case of accidental release, it is important to use appropriate PPE, prevent dust formation, and clean up spills using electrically protected vacuum cleaners or by wet-brushing. Collect material in suitable containers for disposal. Waste disposal must be carried out in accordance with local, regional, and national regulations. As a chemical intermediate manufacturer, we recommend consulting the full Safety Data Sheet for detailed emergency response information.

When sourcing chemicals, it is vital to work with suppliers who provide comprehensive safety documentation. By understanding and adhering to these guidelines, users can safely and effectively utilize 3-Ethynylpyridine in their research and production processes. Always prioritize safety and consult the SDS provided by your chemical supplier.