Hematoxylin, known scientifically by its CAS number 517-28-2, is more than just a dye; it's a chemical marvel that has been central to biological visualization for over a century. As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Hematoxylin that enables researchers and histologists to leverage its unique scientific properties effectively.

At its core, Hematoxylin is a natural compound extracted from the heartwood of the logwood tree. In its pure form, it is a white crystalline powder. However, its staining prowess is unlocked through a process of oxidation, typically using mild oxidizers like sodium iodate, to form hematein. Hematein is the active chromophore. The magic truly happens when hematein complexes with a metal ion, most commonly aluminum (Al³⁺), to form a 'hemalum' lake. This positively charged complex, known as a cation dye, has a strong affinity for negatively charged cellular components. In histological staining, these are primarily the acidic nucleic acids within the cell nucleus (DNA and RNA), as well as acidic mucins and other basophilic structures.

The mechanism allows Hematoxylin to selectively stain nuclei a characteristic blue-purple color, while other counterstains like eosin target the cytoplasm and extracellular matrix, resulting in pink hues. This differentiation is fundamental to understanding tissue morphology and identifying pathological changes. The specific formulation and pH of the staining solution, along with the choice of mordant, can modulate the intensity and specificity of the staining, leading to various types of Hematoxylin stains used in practice, such as Gill's or Mayer's.

For laboratories that need to buy Hematoxylin, understanding these scientific principles highlights the importance of sourcing from a reliable manufacturer. Our Hematoxylin (CAS 517-28-2) is produced to ensure optimal purity and consistent chemical properties, guaranteeing predictable performance in H&E staining, Papanicolaou staining, and various research applications. We serve as a dedicated supplier and manufacturer in China, offering this vital scientific reagent at competitive prices.

By choosing NINGBO INNO PHARMCHEM CO.,LTD. for your Hematoxylin needs, you are investing in a reagent that is backed by a deep understanding of its chemistry and application. Contact us to learn more about how our Hematoxylin can enhance your laboratory's staining protocols and research outcomes.