In the rapidly advancing field of biotechnology and molecular biology, the consistent availability of high-quality reagents is paramount. For researchers and companies engaged in oligonucleotide synthesis, securing a reliable supply chain for essential building blocks, such as phosphoramidites, is a strategic imperative. One such critical reagent is 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite (CAS: 102691-36-1), a compound indispensable for the efficient and accurate synthesis of DNA and RNA sequences.

This article aims to guide procurement managers and R&D scientists in understanding the importance of this phosphoramidite and how to secure a dependable source. As a leading manufacturer and supplier, we recognize the challenges faced by our clients in maintaining production and research continuity. Therefore, we focus on providing not just a product, but a reliable partnership.

Why is 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite Crucial?

2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is a cornerstone reagent in the automated solid-phase synthesis of oligonucleotides. Its phosphoramidite structure allows for the precise addition of nucleotide units, forming the phosphodiester backbone of DNA and RNA strands. The diisopropylamino leaving group is easily cleaved, facilitating highly efficient coupling reactions with activated nucleosides. This characteristic makes it a preferred choice over many other phosphitylating agents due to its improved stability and cost-effectiveness.

For those looking to buy these critical reagents, understanding the specifications is key. Typically, this compound appears as a colorless transparent liquid with a purity exceeding 95%. Its consistent quality is vital for achieving high yields and the required purity in synthesized oligonucleotides, whether for diagnostic, therapeutic, or research applications.

Navigating the Supply Chain: Partnering with Reliable Manufacturers

When sourcing such specialized chemicals, it is crucial to partner with reputable manufacturers and suppliers. A reliable manufacturer not only ensures product quality but also guarantees timely delivery and consistent availability, which is essential for uninterrupted research and production schedules. As a dedicated manufacturer based in China, we pride ourselves on our stringent quality control measures and our ability to meet the demands of global clients.

We understand that for purchasing managers, price is a significant consideration. However, it should not come at the expense of quality or reliability. We offer competitive pricing for 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite, ensuring that your budget is met without compromising on the integrity of your synthesis processes.

Key Considerations for Procurement:

  • Purity and Consistency: Always verify the purity specifications (typically ≥95%) and ensure lot-to-lot consistency.
  • Supplier Reputation: Choose manufacturers with a proven track record in producing high-quality phosphoramidites and other specialty chemicals.
  • Availability and Lead Times: Confirm the supplier's production capacity and their ability to meet your projected demand.
  • Technical Support: A knowledgeable technical support team can provide invaluable assistance for application-specific queries.

By focusing on these aspects, you can make informed decisions when purchasing 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite. We are committed to supporting your scientific endeavors by providing this essential reagent with the highest standards of quality and service. Feel free to contact us to discuss your specific requirements and explore how we can fulfill your needs as your trusted supplier.