Sodium Dichloroacetate: A Key Fine Chemical for Pharmaceutical Research
In the realm of pharmaceutical research and development, high-quality chemical intermediates are indispensable. Sodium Dichloroacetate (DCA), identified by CAS number 2156-56-1, stands out as a crucial fine chemical with a white powder appearance and a purity of 99.0%min. Its solubility in cold water and a melting point of 198°C make it manageable for laboratory use. Beyond its basic chemical properties, DCA's true value lies in its significant biological activities, particularly its impact on cellular metabolism and its potential role in combating diseases like cancer.
DCA's primary mechanism of action involves inhibiting pyruvate dehydrogenase kinase (PDK), thereby influencing the balance between glycolysis and oxidative phosphorylation. This metabolic modulation is of keen interest in cancer research, as many cancer cells exhibit altered metabolic pathways, often relying heavily on glycolysis (the Warburg effect). By promoting a shift towards oxidative phosphorylation, DCA can disrupt cancer cell energy production and potentially induce apoptosis. This makes it a valuable tool for scientists investigating new anti-cancer strategies and exploring novel drug targets.
Furthermore, DCA's application extends to understanding disease mechanisms and developing therapeutic interventions. Its ability to inhibit cell growth without causing programmed cell death (apoptosis) in certain contexts, coupled with its generally favorable safety profile for conditions like lactic acidosis, makes it an attractive candidate for further investigation. The synergy observed when DCA is combined with other therapeutic agents, such as metformin, further underscores its importance as a research chemical.
As a leading supplier of fine chemicals from China, we provide Sodium Dichloroacetate to researchers and pharmaceutical companies worldwide. Our commitment to quality ensures that the DCA we supply meets stringent purity standards, crucial for reproducible and reliable research outcomes. Whether used in initial screening assays, mechanistic studies, or as a building block for more complex molecules, DCA plays a vital role in advancing pharmaceutical science.
In essence, Sodium Dichloroacetate is more than just a chemical compound; it is an enabler of scientific discovery. Its unique properties and diverse applications, particularly in the critical field of cancer therapy research, solidify its position as an indispensable fine chemical intermediate for the pharmaceutical industry.
DCA's primary mechanism of action involves inhibiting pyruvate dehydrogenase kinase (PDK), thereby influencing the balance between glycolysis and oxidative phosphorylation. This metabolic modulation is of keen interest in cancer research, as many cancer cells exhibit altered metabolic pathways, often relying heavily on glycolysis (the Warburg effect). By promoting a shift towards oxidative phosphorylation, DCA can disrupt cancer cell energy production and potentially induce apoptosis. This makes it a valuable tool for scientists investigating new anti-cancer strategies and exploring novel drug targets.
Furthermore, DCA's application extends to understanding disease mechanisms and developing therapeutic interventions. Its ability to inhibit cell growth without causing programmed cell death (apoptosis) in certain contexts, coupled with its generally favorable safety profile for conditions like lactic acidosis, makes it an attractive candidate for further investigation. The synergy observed when DCA is combined with other therapeutic agents, such as metformin, further underscores its importance as a research chemical.
As a leading supplier of fine chemicals from China, we provide Sodium Dichloroacetate to researchers and pharmaceutical companies worldwide. Our commitment to quality ensures that the DCA we supply meets stringent purity standards, crucial for reproducible and reliable research outcomes. Whether used in initial screening assays, mechanistic studies, or as a building block for more complex molecules, DCA plays a vital role in advancing pharmaceutical science.
In essence, Sodium Dichloroacetate is more than just a chemical compound; it is an enabler of scientific discovery. Its unique properties and diverse applications, particularly in the critical field of cancer therapy research, solidify its position as an indispensable fine chemical intermediate for the pharmaceutical industry.
Perspectives & Insights
Future Origin 2025
“Whether used in initial screening assays, mechanistic studies, or as a building block for more complex molecules, DCA plays a vital role in advancing pharmaceutical science.”
Core Analyst 01
“In essence, Sodium Dichloroacetate is more than just a chemical compound; it is an enabler of scientific discovery.”
Silicon Seeker One
“Its unique properties and diverse applications, particularly in the critical field of cancer therapy research, solidify its position as an indispensable fine chemical intermediate for the pharmaceutical industry.”