For procurement managers and R&D scientists in the chemical and pharmaceutical industries, sourcing high-quality intermediates is paramount. One such critical compound is 1,1-Difluoroacetone, also known by its CAS number 431-05-0. This fluorinated ketone is a versatile building block, crucial for various synthesis pathways. Understanding where and how to buy this chemical can significantly impact project timelines and success rates.

Understanding 1,1-Difluoroacetone (CAS 431-05-0)

1,1-Difluoroacetone (C3H4F2O) is recognized for its unique chemical properties, stemming from the presence of two fluorine atoms. Its molecular weight is approximately 94.06 g/mol. As a flammable liquid with a low flash point (around 1.6°C), it requires careful handling and storage, which is standard practice for specialized chemical suppliers. Its primary utility lies in its role as a reactive intermediate in organic synthesis, particularly in the development of new materials, pharmaceuticals, and agrochemicals.

Key Considerations When Purchasing 1,1-Difluoroacetone

When you are looking to purchase 1,1-difluoroacetone, several factors should guide your decision. Firstly, purity is critical. While some sources may list a purity of 90%, striving for higher purity is often beneficial for sensitive research and complex synthesis. Secondly, supplier reliability is non-negotiable. You need a manufacturer or supplier that can consistently deliver the product without compromising quality or lead times. Thirdly, technical support and documentation, such as Safety Data Sheets (SDS) and Certificates of Analysis (CoA), are essential for safe handling and regulatory compliance.

Finding a Trusted 1,1-Difluoroacetone Manufacturer and Supplier in China

China has emerged as a significant global hub for chemical manufacturing, offering a wide range of intermediates at competitive prices. For 1,1-difluoroacetone, identifying a reputable manufacturer in China means looking for companies with a proven track record in fluorochemicals. These suppliers often specialize in building blocks for the pharmaceutical and agrochemical sectors. When you search for a '1,1-difluoroacetone supplier in China,' prioritize those who emphasize quality control, have transparent pricing, and offer responsive customer service. Engaging with these suppliers early in your research phase can help you secure the best price for bulk purchases or recurring orders.

Applications and Market Trends

The demand for 1,1-difluoroacetone is closely linked to advancements in drug discovery and the creation of new crop protection agents. Pharmaceutical companies utilize it as a key intermediate in synthesizing novel drug candidates, aiming to improve efficacy and reduce side effects. In agrochemicals, its incorporation can lead to more potent and environmentally friendly pesticides. For anyone in these fields looking to innovate, securing a consistent supply of this compound is a strategic imperative. If you are planning a project that requires this chemical, it's advisable to request a quote from multiple established suppliers to compare offerings and ensure you are getting optimal value.

In conclusion, when it comes to buying 1,1-difluoroacetone, a thorough evaluation of product specifications, supplier reputation, and pricing is key. By focusing on trusted manufacturers and suppliers, you can ensure the success of your chemical synthesis endeavors.