For procurement managers and R&D scientists in the chemical and pharmaceutical industries, sourcing high-quality intermediates is paramount. 2-(4-cyanopyridin-2-yl)pyridine-4-carbonitrile, identified by CAS number 67491-43-4, is one such critical compound. Its unique structure, featuring a bipyridine core functionalized with cyano groups, makes it an invaluable building block in advanced organic synthesis and materials science. This article aims to guide potential buyers on sourcing this compound, focusing on its synthesis, applications, and the advantages of working with reputable manufacturers in China.

Understanding the Compound: Synthesis and Properties

2-(4-cyanopyridin-2-yl)pyridine-4-carbonitrile (also known as 4,4'-Dicyano-2,2'-bipyridine) has a molecular formula of C12H6N4 and a molecular weight of approximately 206.20 g/mol. It typically presents as a solid with a high purity, often exceeding 97%. Several synthetic routes exist for this compound. Multi-step syntheses commonly involve the oxidation of 2,2'-bipyridine to its N,N'-dioxide, followed by cyanation. Alternatively, one-step palladium-catalyzed coupling reactions of 4-cyanopyridine offer a more direct approach, though yields can vary. Purification techniques such as column chromatography and recrystallization are essential to achieve the high purity required for most applications. For industrial scale-up, manufacturers focus on optimizing these processes for efficiency, cost-effectiveness, and environmental safety.

Key Applications Driving Demand

The demand for 2-(4-cyanopyridin-2-yl)pyridine-4-carbonitrile is driven by its versatility across several key sectors:

  • Organic Synthesis: It serves as a crucial intermediate in the synthesis of more complex organic molecules, finding use in research and development laboratories for creating novel compounds.
  • Materials Science: The electron-withdrawing cyano groups and the bipyridine scaffold make it an excellent ligand for metal complexes and a building block for functional materials, including organic semiconductors and optoelectronic devices.
  • Pharmaceutical Intermediates: Its structure lends itself to being incorporated into potential drug candidates, making it a valuable compound for pharmaceutical R&D departments looking to buy specialized intermediates.
  • Catalyst Development: As a bipyridine derivative, it is frequently employed in the design of ligands for transition metal catalysts, crucial for various industrial chemical transformations.

Sourcing Strategies: Finding a Reliable Manufacturer

When looking to buy 2-(4-cyanopyridin-2-yl)pyridine-4-carbonitrile, especially in bulk quantities, identifying a reliable manufacturer is key. Companies specializing in fine chemical intermediates and custom synthesis are your best bet. For procurement managers, focusing on suppliers based in China can offer significant advantages due to the country's robust chemical manufacturing infrastructure. When evaluating potential suppliers, consider the following:

  • Purity and Quality Control: Ensure the supplier can consistently provide material meeting your purity specifications (e.g., 97% min). Requesting Certificates of Analysis (CoA) is standard practice.
  • Manufacturing Capabilities: Verify their ability to produce the required quantities, from R&D samples to commercial batches. Understanding their synthetic routes and scale-up expertise is beneficial.
  • Pricing and Delivery: Competitive pricing is crucial. Additionally, inquire about lead times and shipping options to ensure timely delivery for your projects. Many suppliers offer free samples for initial evaluation, which is an excellent way to assess quality before committing to a larger purchase.
  • Technical Support: A good supplier will offer technical support, assisting with any queries regarding product specifications, applications, or handling.

As a leading manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality 2-(4-cyanopyridin-2-yl)pyridine-4-carbonitrile. We understand the needs of researchers and industrial buyers for reliable, cost-effective chemical sourcing. By partnering with us, you gain access to a trusted supplier committed to excellence in chemical manufacturing and customer service. If you are looking to buy this essential organic intermediate, we encourage you to contact us for a competitive quote and a free sample.