For procurement managers and R&D scientists in the chemical and pharmaceutical industries, sourcing high-quality intermediates is paramount. 2-Benzofurancarboxaldehyde (CAS 4265-16-1) stands out as a critical heterocyclic building block, vital for numerous organic synthesis pathways, particularly in the development of pharmaceutical agents and specialized fine chemicals. Understanding its properties and how to procure it efficiently is key to successful project outcomes. As a prominent manufacturer and supplier based in China, we aim to demystify the process of acquiring this essential compound.

Understanding 2-Benzofurancarboxaldehyde (CAS 4265-16-1)

2-Benzofurancarboxaldehyde is an aromatic aldehyde characterized by its benzofuran core structure. Its chemical formula is C9H6O2, and it possesses a molecular weight of approximately 146.14 g/mol. Typically appearing as a transparent yellow to brown liquid, it has a melting point around 9-9.5 °C and a boiling point of 135 °C at 18 mmHg. Its distinctive bitter almond odor is a notable characteristic. Its limited solubility in water and good stability under normal conditions make it a manageable reagent for various laboratory and industrial processes. The purity of this compound is often a critical factor; most suppliers offer it at a minimum of 95% purity, with higher grades available for specialized applications.

Key Applications in Synthesis

The primary utility of 2-Benzofurancarboxaldehyde lies in its role as a versatile intermediate in organic synthesis. It is notably employed in the preparation of isoxazolines, a class of heterocyclic compounds with significant pharmacological interest. Researchers are also investigating its use in the synthesis of more complex molecules, such as (E)-3-(benzofuran-2′-ylmethylidene)-1-methyl-2-indolinone and 1-(benzofuran-2-yl)methanol. Its aldehyde functional group readily participates in various condensation and addition reactions, making it an attractive starting material for medicinal chemists and organic synthesis specialists. If you are looking to buy these types of advanced intermediates, understanding the nuances of their application is crucial.

Procurement Strategies for 2-Benzofurancarboxaldehyde

When sourcing 2-Benzofurancarboxaldehyde (CAS 4265-16-1), several factors come into play for B2B buyers. The price of 2-Benzofurancarboxaldehyde is a significant consideration, and manufacturers in China often offer competitive pricing due to economies of scale and efficient production processes. Prospective buyers should always look for suppliers who can provide detailed Certificates of Analysis (CoA) to verify purity and specifications. It's also advisable to inquire about sample availability for initial testing. For bulk purchases, establishing a direct relationship with a reliable manufacturer can ensure consistent supply, quality control, and better negotiation power on price. Searching for '2-benzofurancarboxaldehyde price in China' or 'cas 4265-16-1 supplier' can help identify potential partners.

Furthermore, consider the supplier's capacity for custom synthesis if your project requires specific modifications or higher purities not readily available. A reputable manufacturer will not only offer a standard product but also the flexibility to meet unique project demands. Engaging with a supplier that understands the importance of supply chain stability and offers responsive customer service, including efficient logistics and after-sales support, is vital for long-term collaboration. When you need to buy this key heterocyclic intermediate, partnering with an experienced manufacturer in China provides a strategic advantage.

In conclusion, 2-Benzofurancarboxaldehyde (CAS 4265-16-1) is a compound of significant value in chemical synthesis. By understanding its properties, applications, and engaging with trusted manufacturers and suppliers in China, businesses can secure a reliable source of this essential building block, driving innovation in pharmaceutical and fine chemical industries.