For Research and Development scientists, selecting the right chemical intermediates can significantly impact the success and efficiency of synthetic projects. 2-Chlorobenzotrifluoride (CAS: 88-16-4) is a compound that consistently proves its value in organic synthesis laboratories due to its unique structural features and reactivity. This article provides R&D scientists with key insights into sourcing and utilizing this important chemical intermediate.

Understanding the Chemical Profile of 2-Chlorobenzotrifluoride

2-Chlorobenzotrifluoride is an aromatic compound with a chlorine atom and a trifluoromethyl group attached to a benzene ring. This combination offers several advantages for synthetic chemists:

  • Reactivity: The chlorine atom can undergo various nucleophilic substitution reactions, while the trifluoromethyl group is electron-withdrawing, influencing the reactivity of the aromatic ring and potentially enhancing the stability or lipophilicity of the resulting molecules.
  • Solubility: Its relatively non-polar nature makes it soluble in many organic solvents, which is convenient for reaction setup and workup.
  • Applications in Synthesis: It is widely recognized as an intermediate in the production of agrochemicals, such as the rodenticide Bromethalin, and is also critical in the synthesis of certain pharmaceutical compounds. Its presence is often found in molecules designed for specific biological activities.

Essential Specifications for R&D Purchases

When ordering 2-Chlorobenzotrifluoride for research purposes, scientists typically look for:

  • High Purity: An assay of 99% or higher is generally preferred to minimize side reactions and ensure reproducible results. Purity levels such as ≥99.0% or ≥99.8% are commonly specified.
  • Reliable CAS Number: Confirming the CAS number as 88-16-4 is crucial for identification.
  • Small Pack Sizes: For laboratory use, purchasing in smaller quantities (e.g., grams to kilograms) is often necessary.
  • Batch-to-Batch Consistency: A supplier that can demonstrate consistent quality across different batches is highly valued for long-term research projects.

Researchers often need to purchase 2-Chlorobenzotrifluoride for various synthetic transformations, including:

  • Building complex fluorinated organic molecules.
  • Synthesizing intermediates for pesticide and herbicide development.
  • Developing new pharmaceutical candidates with specific pharmacological profiles.
  • As a reference standard in analytical chemistry.

Choosing a Supplier for Your Lab

For R&D scientists, the choice of supplier for 2-Chlorobenzotrifluoride involves not just price but also reliability and quality. When evaluating suppliers, consider:

  • Supplier Reputation: Look for manufacturers with a strong history of supplying quality chemicals to research institutions.
  • Product Documentation: Availability of safety data sheets (SDS) and certificates of analysis (CoA) is essential for lab safety and experimental integrity.
  • Delivery Speed: For time-sensitive research, quick turnaround and reliable shipping are critical.
  • Customer Service: Responsive customer support can be invaluable when questions arise about product specifications or availability.

By carefully selecting your source for 2-Chlorobenzotrifluoride, R&D scientists can ensure their synthetic endeavors are built on a foundation of reliable, high-quality chemical intermediates. We are a dedicated manufacturer and supplier ready to meet your research needs for this essential compound.