For procurement managers and R&D scientists in the pharmaceutical, agrochemical, and fine chemical industries, securing a reliable source of high-purity intermediates is paramount. Among these critical materials is 2,6-Difluoro-4-hydroxybenzonitrile (CAS: 123843-57-2), a versatile building block with significant applications. This guide aims to assist buyers in understanding its specifications, applications, and how to effectively source this compound from reputable manufacturers and suppliers.

2,6-Difluoro-4-hydroxybenzonitrile, often referred to by its synonym 4-Cyano-3,5-difluorophenol, is characterized by its white to off-white crystalline powder appearance and a high assay of ≥98.0%. These specifications are crucial for applications where purity directly impacts the efficacy and outcome of subsequent synthesis steps. Its melting point of 127°C and stable chemical nature further enhance its utility in various chemical processes.

The primary applications of 2,6-Difluoro-4-hydroxybenzonitrile span several key industries:

Pharmaceutical Intermediates: Its fluorinated aromatic structure makes it an excellent precursor for developing novel drug molecules. The introduction of fluorine can improve metabolic stability, enhance membrane permeability, and fine-tune the biological activity of APIs. Researchers frequently search for this compound to buy for specific drug synthesis pathways.

Agrochemical Intermediates: In the agrochemical field, this compound is used to synthesize advanced pesticides, herbicides, and fungicides. Its incorporation can lead to products with improved efficacy, selectivity, and environmental profiles, supporting the need for effective crop protection.

Dyes and Pigments: The unique electronic properties conferred by the fluorine atoms and nitrile group make it valuable in creating specialty dyes and pigments with distinct color characteristics and superior performance.

General Organic Synthesis: As a broad organic synthesis intermediate, it enables the construction of complex molecular architectures for research and development across various chemical disciplines.

When sourcing 2,6-Difluoro-4-hydroxybenzonitrile, several factors are critical for procurement managers:

1. Purity and Specifications: Always verify that the supplier can consistently provide material meeting the required assay (≥98.0%) and physical form. Requesting a Certificate of Analysis (CoA) is standard practice.

2. Supplier Reliability: Look for established manufacturers and suppliers with a proven track record in the chemical industry. Companies offering stable supply chains and responsive customer service are invaluable.

3. Pricing and Packaging: Competitive pricing, especially for bulk purchases or wholesale inquiries, is essential. Discuss packaging options, typically 25 kg drums, but inquire about customized solutions to meet your operational needs.

4. Manufacturing Capabilities: Understanding the manufacturer's expertise in fluorinated compounds and their quality control processes can provide confidence in the product's origin and consistency.

For those looking to purchase 2,6-Difluoro-4-hydroxybenzonitrile, consider partnering with manufacturers and suppliers based in China. These suppliers often provide a strong combination of competitive price, large-scale production capacity, and a commitment to quality. When searching for a “2,6-difluoro-4-hydroxybenzonitrile manufacturer China” or a “cas 123843-57-2 supplier,” prioritize companies that demonstrate transparency and robust technical support. Engaging with such a supplier ensures you receive a dependable supply of this vital intermediate for your ongoing projects and production demands.