For procurement managers and R&D scientists in the chemical and pharmaceutical industries, sourcing high-quality intermediates is paramount. This guide focuses on 4-(Trifluoromethoxy)benzaldehyde (CAS 659-28-9), a crucial building block for numerous organic synthesis pathways. Understanding its properties, applications, and reliable supply chains is key to successful procurement.

What is 4-(Trifluoromethoxy)benzaldehyde?

4-(Trifluoromethoxy)benzaldehyde is an aromatic aldehyde characterized by a trifluoromethoxy group attached to the benzene ring at the para position. Its molecular formula is C8H5F3O2, and it has a molecular weight of 190.11900. Typically appearing as a colorless to yellow liquid, this compound is valued for its reactivity and the unique properties conferred by the trifluoromethoxy substituent. Its physical properties, such as a boiling point of 93°C and a flash point of 70°C, are important considerations for safe handling and storage.

Key Applications in Organic Synthesis

The primary use of 4-(Trifluoromethoxy)benzaldehyde lies in its role as an intermediate for organic synthesis. It serves as a versatile precursor in the creation of:

  • Pharmaceuticals: As a building block for active pharmaceutical ingredients (APIs), contributing to the development of new drugs. Scientists looking to buy this for drug discovery will find its structure beneficial for introducing the trifluoromethoxy moiety.
  • Agrochemicals: In the synthesis of pesticides and herbicides, where the trifluoromethoxy group can enhance efficacy and stability. Formulators seeking advanced crop protection solutions may purchase this intermediate.
  • Specialty Chemicals: For the creation of advanced materials and fine chemicals used in various industrial applications.

When you need to buy this chemical, focusing on its purity, often specified as ≥99.0% via GC, is critical for achieving reliable results in synthesis.

Where to Buy 4-(Trifluoromethoxy)benzaldehyde: Sourcing from China Manufacturers

For businesses seeking a reliable supplier of 4-(Trifluoromethoxy)benzaldehyde, China offers numerous manufacturers and suppliers. When you choose to buy from established Chinese chemical suppliers, you often benefit from competitive pricing and a wide range of product specifications. It's advisable to partner with manufacturers who provide detailed product specifications, certificates of analysis (CoA), and ensure consistent quality. Look for suppliers who can offer bulk quantities and understand international shipping requirements. When inquiring about price, be sure to specify your required purity and quantity.

Storage and Handling Recommendations

To maintain the quality and reactivity of 4-(Trifluoromethoxy)benzaldehyde, proper storage is essential. It should be stored in a cool, well-ventilated place, away from direct sunlight and incompatible materials. Following these guidelines ensures that the product remains stable and ready for use in your synthesis processes, making it a dependable component for any R&D or manufacturing operation. Procurement managers should ensure their facilities comply with these recommended storage conditions.

In conclusion, 4-(Trifluoromethoxy)benzaldehyde is a vital chemical intermediate with diverse applications. By understanding its properties and strategically sourcing it from reputable manufacturers, particularly those in China, you can ensure the success of your organic synthesis projects. For those looking to buy, focusing on purity and supplier reliability is key.