Chromatography is a cornerstone of analytical chemistry, enabling the separation and identification of complex mixtures. The choice of stationary phase is critical to achieving effective separation. Squalane (CAS 111-01-3), a stable and inert hydrocarbon, has long been recognized for its utility as a non-polar stationary phase, particularly in gas chromatography (GC). As a specialized manufacturer and supplier in China, we provide high-purity Squalane that meets the demands of analytical laboratories. This article highlights the role of Squalane in chromatography and the advantages of sourcing it from a trusted chemical provider.

Squalane as a Non-Polar Stationary Phase

Squalane, a saturated form of squalene, is characterized by its lack of double bonds, which confers remarkable chemical stability and resistance to oxidation. Its molecular structure is a long, branched alkane chain, making it inherently non-polar. This non-polar nature dictates its interaction with analytes in chromatographic separations.

In GC, Squalane is typically used as a liquid stationary phase coated onto a solid support material. Its primary function is to interact with non-polar analytes through dispersion forces. Compounds that are more soluble in the stationary phase will be retained longer on the column, leading to their separation from less soluble compounds. Key characteristics that make Squalane valuable in this application include:

  • Inertness: Squalane does not readily react with the analytes or the mobile phase, ensuring that the separation is based purely on the physical interactions between the analyte and the stationary phase. This minimizes the risk of unwanted side reactions or column degradation.
  • High Thermal Stability: Squalane can withstand relatively high temperatures commonly employed in GC, allowing for the analysis of volatile and semi-volatile compounds without premature degradation of the stationary phase.
  • Non-Polarity: This makes Squalane particularly effective for separating general hydrocarbons, alkanes, and other non-polar organic compounds. It provides a baseline polarity close to zero, serving as a benchmark for assessing the polarity of other stationary phases.
  • Consistent Performance: The stability of Squalane ensures that chromatographic columns coated with it provide reproducible and reliable results over time, which is essential for quantitative analysis and method validation.

Applications in Analytical Chemistry

Squalane-based columns are widely used for:

  • Petroleum analysis: Separating various hydrocarbon fractions in crude oil and refined products.
  • Analysis of non-polar solvents and compounds: Ensuring the purity of solvents or identifying non-polar contaminants.
  • Environmental monitoring: Detecting and quantifying non-polar pollutants in air and water samples.
  • Research and development: Investigating the composition of complex organic mixtures.

Why Choose Our Squalane?

For analytical laboratories and researchers, reliable sourcing of high-purity Squalane is critical. As a dedicated chemical supplier in China, we offer:

  • High Purity: Our Squalane is manufactured to meet exacting purity standards, ensuring optimal performance in sensitive chromatographic applications. When you buy Squalane from us, you are investing in reliable analytical results.
  • Competitive Pricing: We provide Squalane at competitive prices, making advanced analytical techniques more accessible for research institutions and commercial laboratories.
  • Consistent Supply: Our manufacturing capabilities ensure a steady and reliable supply of Squalane, preventing disruptions to your laboratory's workflow.
  • Technical Data: We provide comprehensive technical specifications and support to assist in selecting and utilizing Squalane effectively.

We invite analytical chemists and procurement managers to inquire about our Squalane (CAS 111-01-3) for their chromatographic needs. Contact us today to receive a quote and discuss how our high-quality Squalane can enhance your analytical capabilities.