NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing in-depth information on the chemical compounds we supply, fostering a deeper understanding of their synthesis and application. N,N'-Bis(Acryloyl)Cystamine (CAS: 60984-57-8), or BAC, is a compound of significant interest due to its versatile chemical properties and wide-ranging applications.

The synthesis of N,N'-Bis(Acryloyl)Cystamine typically involves the reaction of cystamine (a diamine) with acryloyl chloride or a similar acrylic acid derivative. This acylation process attaches the acryloyl groups to the amine functionalities of cystamine, forming the characteristic bis-acrylamide structure. The crucial element, the disulfide bond (-S-S-), is inherited from the cystamine precursor. This specific synthetic route allows for the controlled production of BAC with high purity, which is essential for its performance in sensitive applications.

Understanding the properties of BAC is key to its effective utilization. Its molecular formula is C10H16N2O2S2, and it has a molecular weight of approximately 260.38 g/mol. Physically, it often appears as an off-white solid. The melting point typically falls within the range of 121-125 °C, with some sources reporting specific values like 123-124 °C. While slightly soluble in water, it demonstrates better solubility in organic solvents like acetic acid, as reported by various scientific suppliers.

The most significant property of BAC is the redox-responsiveness of its disulfide bond. This bond can be readily cleaved by reducing agents, such as dithiothreitol (DTT), thiols, or glutathione. This cleavage converts the disulfide into two free thiol (-SH) groups. This reversible reaction is the basis for its application as a cleavable cross-linker in various polymer systems, including polyacrylamide gels used in electrophoresis and in the formation of stimuli-responsive hydrogels for drug delivery. The ability to break and potentially reform these bonds offers a degree of control over material architecture and release mechanisms.

At NINGBO INNO PHARMCHEM CO.,LTD., we ensure that the BAC we provide meets rigorous quality standards, guaranteeing the purity and chemical integrity necessary for reliable chemical synthesis for drug delivery, polymer modification, and other advanced research. Our expertise in chemical synthesis supports researchers in accessing the materials they need to drive scientific discovery.

In conclusion, the synthesis and properties of N,N'-Bis(Acryloyl)Cystamine, particularly its redox-sensitive disulfide bond, make it an indispensable reagent for scientists and engineers working at the forefront of material science and biotechnology.