For chemists and product formulators working in advanced material science and organic synthesis, understanding the nuances of key chemical building blocks is essential. 2-Acetyl-4-chlorothiophene, identified by its CAS number 34730-20-6, is one such compound that offers significant utility due to its functional groups and thiophene core. This article aims to provide insight into its synthesis, properties, and diverse applications, highlighting the benefits of sourcing from reputable Chinese manufacturers.

The synthesis of 2-Acetyl-4-chlorothiophene typically involves established chemical processes, often starting from readily available thiophene derivatives. Manufacturers in China employ precise reaction conditions to achieve high purity, usually ensuring the product is a light yellow liquid with a purity of 98% or higher. Its molecular formula is C6H5ClOS, with a molecular weight of 160.62. This intermediate's structure, featuring an acetyl group and a chlorine atom on a thiophene ring, makes it a versatile starting material for creating more complex molecules.

The applications of 2-Acetyl-4-chlorothiophene span across several industries. In organic synthesis, it serves as a valuable synthon for introducing thiophene moieties into larger molecular frameworks. This is particularly relevant in the development of new agrochemicals, dyes, and importantly, pharmaceutical intermediates. Researchers often look to purchase this compound for its role in Palladium-catalyzed cross-coupling reactions, which are fundamental in modern synthetic chemistry. The ability to modify the thiophene ring at specific positions allows for tailored synthesis of target compounds.

For procurement professionals, securing a reliable supply of 2-Acetyl-4-chlorothiophene is crucial for continuous R&D and production. Chinese manufacturers are well-positioned to offer this intermediate at competitive prices, especially when purchased in bulk. When sourcing, it's advisable to request detailed technical data sheets and safety information, given its classification as a hazardous material. Partnering with an established supplier ensures not only cost-effectiveness but also adherence to quality standards, vital for applications where precision is key.

In summary, 2-Acetyl-4-chlorothiophene is a compound of significant chemical interest, offering substantial versatility in synthesis. By understanding its properties and collaborating with trusted Chinese manufacturers, R&D teams can effectively leverage this intermediate for innovation in pharmaceuticals, materials, and fine chemicals. Make sure to request a quote from a reliable supplier to procure this essential chemical.