For professionals in the chemical and pharmaceutical industries, understanding the origin and manufacturing process of key intermediates like Stearoyl Chloride (CAS 112-76-5) provides critical insight into product quality and supply reliability. As a manufacturer and supplier of this versatile acyl chloride, we aim to offer transparency into how our high-purity, yellow transparent oily liquid is produced. This knowledge empowers our clients to make informed purchasing decisions and ensures they receive a product that meets stringent specifications.

The Fundamental Reaction: Converting Stearic Acid to Stearoyl Chloride

The primary method for synthesizing Stearoyl Chloride involves the reaction of stearic acid with a chlorinating agent. Stearic acid, a saturated fatty acid with an 18-carbon chain, is readily available and serves as the organic backbone. The most common chlorinating agents employed in industrial settings include thionyl chloride (SOCl2) or phosphorus pentachloride (PCl5). The reaction replaces the hydroxyl group (-OH) of the carboxylic acid with a chlorine atom (-Cl), yielding Stearoyl Chloride and by-products.

Key Chlorinating Agents and Reaction Conditions

  • Thionyl Chloride (SOCl2): This is a widely used reagent for converting carboxylic acids to acyl chlorides. The reaction typically proceeds smoothly, producing Stearoyl Chloride, sulfur dioxide (SO2), and hydrogen chloride (HCl) as gaseous by-products, which can be easily removed. Often, the reaction is carried out under reflux conditions, sometimes in the presence of a catalyst like dimethylformamide (DMF) to accelerate the process. The typical purity of the resulting Stearoyl Chloride is high, often above 98%.
  • Phosphorus Pentachloride (PCl5): Another effective chlorinating agent, PCl5 reacts with stearic acid to form Stearoyl Chloride, phosphorus oxychloride (POCl3), and HCl. While also efficient, the handling of PCl5 and the separation of POCl3 can sometimes present additional challenges compared to thionyl chloride.

Manufacturing Excellence and Quality Assurance

At our facility, we employ advanced manufacturing processes to ensure the highest quality Stearoyl Chloride. Strict control over reaction parameters, including temperature, pressure, and reagent addition rates, is maintained. Following the synthesis, purification steps are critical to remove any residual reactants, by-products, and to achieve the desired 98%+ assay. Our quality assurance team rigorously tests each batch using methods like GC (Gas Chromatography) and titration to verify purity, appearance, and other key specifications. This commitment ensures that when you buy Stearoyl Chloride from us, you receive a product that consistently meets your demanding application requirements.

Choosing a Reliable Supplier for Your Needs

Understanding the manufacturing process underscores the importance of sourcing from experienced and quality-focused suppliers. As a leading manufacturer and supplier of Stearoyl Chloride in China, we are dedicated to delivering excellence. We offer competitive pricing, reliable supply, and comprehensive documentation, including SDS and COA. If your industrial processes require high-purity Stearoyl Chloride for applications such as pharmaceutical synthesis, surfactant production, or antitumor agent development, we are your trusted partner. Contact us to discuss your procurement needs and experience the quality and service we provide.