For chemical engineers, R&D scientists, and procurement professionals, a thorough understanding of a compound's properties and safe handling procedures is crucial for successful and efficient utilization. 1-Chloro-2,4,6-trifluorobenzene (CAS 2106-40-3) is a key intermediate used across various industries, particularly in pharmaceuticals and agrochemicals. This article provides a detailed technical overview, covering its physical characteristics, chemical behavior, and essential safety considerations. As a leading manufacturer and supplier, we ensure our product meets the highest standards, but proper handling remains the user's responsibility.

Key Physical and Chemical Properties
1-Chloro-2,4,6-trifluorobenzene is an aromatic halogenated compound with the molecular formula C6H2ClF3 and a molecular weight of approximately 166.53 g/mol. Understanding its properties is vital for its application:

  • Appearance: Typically described as a colorless liquid.
  • Melting Point: Reported between -3°C and -2°C, indicating it can exist as a solid or liquid near room temperature.
  • Boiling Point: Approximately 124°C (literature value). This moderate boiling point facilitates its use in reactions requiring controlled temperatures.
  • Flash Point: Around 106°F, classifying it as a combustible liquid. Appropriate fire safety measures are essential.
  • Density: Approximately 1.463 g/mL at 25°C, indicating it is denser than water.
  • Refractive Index: n20/D 1.456 (literature value), a standard parameter for purity assessment.
  • Purity: Typically available with a purity of 95% minimum from reputable manufacturers and suppliers.
  • Solubility: While specific data might vary, similar fluorinated aromatics are generally soluble in organic solvents and poorly soluble in water.

Storage and Handling Guidelines
Proper storage and handling are critical to maintain product integrity and ensure safety. As a supplier, we recommend the following:

  • Storage Conditions: Store in a dry, cool, and well-ventilated environment. Keep containers tightly sealed to prevent exposure to air and moisture, which could affect product quality. Storage under inert gas may be recommended for long-term preservation.
  • Handling Precautions: Avoid contact with skin, eyes, and clothing. Wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and protective clothing. Use only in a well-ventilated area or fume hood.
  • Fire Safety: Keep away from heat, sparks, and open flames. In case of fire, use dry chemical, CO2, or foam extinguishing agents. Water spray may be used to cool fire-exposed containers.
  • Chemical Reactivity: Due to the presence of halogens and the aromatic ring, it can participate in various organic reactions, such as nucleophilic aromatic substitution and cross-coupling reactions. Understand its reactivity profile before use.

Safety Data and Regulatory Information
While this article provides general guidance, it is imperative to consult the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) provided by the manufacturer for comprehensive safety information. The SDS will detail hazard classifications, first-aid measures, accidental release measures, and disposal considerations specific to 1-Chloro-2,4,6-trifluorobenzene. Always adhere to local regulations regarding the handling, storage, and disposal of chemical substances. As a responsible supplier, we ensure our product documentation is accurate and accessible.

Conclusion
1-Chloro-2,4,6-trifluorobenzene (CAS 2106-40-3) is a valuable chemical intermediate with well-defined properties. By understanding its physical and chemical characteristics, and by adhering to strict safety and handling protocols, users can maximize its utility in their synthesis processes. Whether you are looking to buy for pharmaceutical research, agrochemical development, or other fine chemical applications, selecting a reputable manufacturer that provides comprehensive technical data and quality assurance is paramount. Contact us to purchase high-quality 1-Chloro-2,4,6-trifluorobenzene and receive the necessary technical support for your projects.