For scientists engaged in complex chemical synthesis, a thorough understanding of the intermediates they use is crucial. 2,3-Dichloro-pyrido[2,3-b]pyrazine (CAS 25710-18-3) is a prime example of a heterocyclic intermediate whose specific properties dictate its suitability for various applications, particularly in pharmaceutical R&D and material science. This technical breakdown aims to provide chemists and researchers with the essential information they need.

Chemical Identity and Structure

2,3-Dichloro-pyrido[2,3-b]pyrazine, with the CAS registry number 25710-18-3, possesses the molecular formula C7H3Cl2N3. Its molecular weight is approximately 200.02 g/mol. The compound features a fused ring system comprising a pyridine ring and a pyrazine ring, with two chlorine atoms strategically positioned on the pyridine moiety. This specific arrangement of atoms and functional groups imparts unique reactivity, making it a valuable building block in organic synthesis. As typically reported, it presents as a white powder.

Key Physical and Chemical Properties

While detailed experimental data can vary, predicted properties for 2,3-Dichloro-pyrido[2,3-b]pyrazine often include:

  • Appearance: White powder
  • Purity: Typically available at ≥95% or ≥99%, which is critical for precise chemical reactions.
  • Melting Point: Predicted around 103.39°C.
  • Boiling Point: Predicted to be approximately 282.3°C at 760 mmHg.
  • Density: Predicted to be around 1.6 g/cm³.

These properties are vital for researchers when planning reaction conditions, purification steps, and storage. The presence of the two chlorine atoms offers sites for nucleophilic substitution reactions, a common strategy in the synthesis of more complex molecules. This reactivity profile makes it an attractive intermediate for creating novel compounds.

Applications in Synthesis and Research

The primary utility of 2,3-Dichloro-pyrido[2,3-b]pyrazine lies in its role as a chemical intermediate. It is frequently employed in:

  • Pharmaceutical Synthesis: As a precursor for APIs, contributing to the development of new drugs.
  • Drug Discovery: A valuable starting material for medicinal chemists exploring novel molecular scaffolds with potential biological activity.
  • Material Science: Used in the design of advanced materials due to its inherent structural and electronic properties.
  • Agrochemical Development: Potentially used in the synthesis of compounds with agricultural applications.

When sourcing this compound, researchers should prioritize suppliers who provide detailed technical specifications and ensure high purity. Purchasing from established manufacturers ensures that the material meets the stringent requirements of advanced scientific research.

Sourcing and Quality Assurance

For R&D scientists, securing a reliable supply of high-purity 2,3-Dichloro-pyrido[2,3-b]pyrazine is essential. When searching for 'buy 2,3-dichloro-pyrido[2,3-b]pyrazine' or '2,3-dichloro-pyrido[2,3-b]pyrazine supplier', prioritize vendors that offer comprehensive technical support, SDS, and CoAs. Companies manufacturing in China are often a cost-effective source, but vetting their quality control processes is crucial. Investing in a quality intermediate ensures that your research findings are accurate and reproducible.

In summary, 2,3-Dichloro-pyrido[2,3-b]pyrazine is a pivotal intermediate with significant potential in various chemical disciplines. Understanding its properties and sourcing it from reliable manufacturers is key to successful research and development.