In the realm of synthetic organic chemistry, certain molecules serve as exceptionally versatile building blocks, enabling the construction of complex and valuable compounds. 4-Bromo-1-butanol (CAS 33036-62-3) is one such molecule, prized for its bifunctional nature which allows for a diverse array of chemical transformations. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated 4-Bromo-1-butanol supplier in China, facilitates access to this crucial intermediate for researchers and manufacturers globally.

Chemical Reactivity of 4-Bromo-1-butanol

The core of 4-Bromo-1-butanol's utility lies in its two reactive sites: the primary hydroxyl (-OH) group and the primary alkyl bromide (-Br). This dual functionality allows it to participate in several key reaction types:

  • Nucleophilic Substitution: The bromine atom is an excellent leaving group, making the terminal carbon susceptible to nucleophilic attack. This allows for the introduction of various functionalities, such as amines, thiols, or other carbon chains, via SN2 reactions.
  • Ether Formation: The hydroxyl group can readily undergo etherification reactions. For instance, reacting with an alcohol under acidic conditions or with an alkyl halide in the presence of a base yields ethers. A notable example is the reaction with dihydropyran to form tetrahydropyranyl ethers, often used as protecting groups.
  • Esterification: The primary alcohol can be esterified with carboxylic acids or acid chlorides to form esters, which are important in various applications, including pharmaceuticals and fragrances.
  • Intramolecular Cyclization: Under appropriate conditions, the hydroxyl group can internally attack the carbon bearing the bromine atom, leading to the formation of tetrahydrofuran, a five-membered cyclic ether.

Applications Driving Demand

The versatility of 4-Bromo-1-butanol makes it indispensable in:

  • Pharmaceutical Synthesis: It's a key intermediate for building complex drug molecules, contributing to the development of new therapies. Researchers often seek to buy 4-Bromo-1-butanol for its role in creating specific heterocyclic structures or adding functionalized side chains.
  • Fine Chemical Manufacturing: Its use extends to the production of various fine chemicals and specialty materials where precise functionalization is required.
  • Organic Synthesis Research: Academic and industrial laboratories utilize it as a starting material for exploring novel synthetic routes and methodologies.

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NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality 4-Bromo-1-butanol (CAS 33036-62-3). As a leading 4-Bromo-1-butanol manufacturer, we offer competitive pricing and ensure a reliable supply chain. Our expertise in producing this vital intermediate allows us to support your research and production needs effectively. When you need to buy 4-Bromo-1-butanol, consider us for quality and consistent supply.

In conclusion, the rich chemical reactivity of 4-Bromo-1-butanol solidifies its position as a foundational molecule in modern organic synthesis. Partner with NINGBO INNO PHARMCHEM CO.,LTD. to unlock its potential for your next chemical innovation.