The Chemistry of 4-Fluorobutanol: Properties and Reactivity
Delving into the fundamental chemistry of a compound is essential for understanding its potential applications and optimizing its use in synthesis. 4-Fluorobutanol (C4H9FO) is a fascinating organic molecule whose unique structure dictates its valuable properties and reactivity. As a leading manufacturer and supplier of specialized chemicals, we offer insights into the chemical profile of 4-Fluorobutanol, a key intermediate for various industries. For those looking to buy this compound, grasping its chemistry is the first step to unlocking its full potential.
The molecular formula of 4-Fluorobutanol, C4H9FO, reveals a four-carbon chain with a hydroxyl group (-OH) at one end and a fluorine atom (-F) at the other. This arrangement is significant. The presence of the hydroxyl group makes it a primary alcohol, capable of undergoing typical alcohol reactions such as esterification, oxidation, and ether formation. However, the terminal fluorine atom imparts unique characteristics. Fluorine is the most electronegative element, and its presence can influence the electron distribution within the molecule, affecting bond strengths and reactivity. This electronegativity can activate adjacent carbon atoms for certain reactions and stabilize transition states.
Key physico-chemical properties further define 4-Fluorobutanol's utility. It is typically a colorless liquid with a distinct odor. Its boiling point of approximately 101.5°C at atmospheric pressure (760 mmHg) and a flash point of around 45.4°C indicate it is a flammable liquid that requires careful handling. Its density is approximately 0.944 g/cm³, and it is soluble in water and miscible with many organic solvents, enhancing its versatility in various reaction media. As a reliable supplier, we ensure these properties are consistent across our product batches, providing you with predictable results.
The reactivity of 4-Fluorobutanol is a major draw for synthetic chemists. The hydroxyl group readily participates in nucleophilic substitution or can be converted into a better leaving group, facilitating reactions. The carbon-fluorine bond, while strong, can also be involved in certain specialized transformations, particularly when the fluorine atom influences the reactivity of neighboring carbons. This dual functionality makes 4-Fluorobutanol an excellent building block for introducing fluorinated fragments into larger molecules. For those seeking to purchase this versatile intermediate, understanding these chemical characteristics is vital for successful synthesis design. We are a dedicated manufacturer in China, ready to provide you with high-quality 4-Fluorobutanol. Request a quote to explore our offerings.
Perspectives & Insights
Silicon Analyst 88
“The presence of the hydroxyl group makes it a primary alcohol, capable of undergoing typical alcohol reactions such as esterification, oxidation, and ether formation.”
Quantum Seeker Pro
“Fluorine is the most electronegative element, and its presence can influence the electron distribution within the molecule, affecting bond strengths and reactivity.”
Bio Reader 7
“This electronegativity can activate adjacent carbon atoms for certain reactions and stabilize transition states.”