The Crucial Role of 2-Morpholinoethanol in Modern Pharmaceutical Synthesis
In the intricate world of pharmaceutical research and development, the availability of high-quality chemical intermediates is paramount. Among these essential compounds, 2-Morpholinoethanol (CAS: 622-40-2) stands out for its versatility and critical role in advancing drug discovery and formulation. NINGBO INNO PHARMCHEM CO.,LTD. recognizes the significance of this compound and is dedicated to providing reliable access to it for researchers and manufacturers worldwide.
2-Morpholinoethanol, also known by synonyms such as 4-Morpholineethanol or N-(2-Hydroxyethyl)morpholine, is a clear, colorless to yellow liquid with a molecular formula of C6H13NO2. Its chemical structure, featuring a morpholine ring with a hydroxyethyl substituent, endows it with unique properties that make it highly sought after in organic synthesis. One of its most prominent applications lies in the preparation of ester prodrugs. Prodrugs are inactive or less active precursors that are converted into their active pharmaceutical ingredients (APIs) within the body. This strategy is employed to enhance drug solubility, improve bioavailability, increase stability, or achieve targeted delivery. By incorporating 2-Morpholinoethanol into the prodrug structure, scientists can fine-tune these pharmacokinetic and pharmacodynamic properties, ultimately leading to more effective and safer therapeutic agents.
The ability of 2-Morpholinoethanol to act as a building block for prodrugs is a testament to its chemical reactivity and functional group compatibility. For instance, it has been utilized in the synthesis of ester prodrugs of naproxen, a well-known nonsteroidal anti-inflammatory drug (NSAID). The esterification process can alter the absorption and distribution characteristics of naproxen, potentially leading to improved patient outcomes. Furthermore, research has indicated that 4-(2-Hydroxyethyl)morpholine can play a role in biological processes, showing potential to induce repair in rat hepatocyte primary culture/DNA. This suggests that beyond its role as a synthetic intermediate, it may possess inherent biological relevance that warrants further investigation.
For professionals seeking to buy 2-Morpholinoethanol, understanding its reliable sourcing is crucial. NINGBO INNO PHARMCHEM CO.,LTD. ensures that the 2-Morpholinoethanol supplied meets stringent quality standards, guaranteeing purity and consistency. This reliability is essential for reproducible experimental results and the successful scale-up of pharmaceutical manufacturing processes. Accessing detailed information, such as the 2-morpholinoethanol safety data sheet, is also vital for proper handling and compliance within laboratory and industrial environments. By providing comprehensive product data and reliable supply, NINGBO INNO PHARMCHEM CO.,LTD. empowers its clients to drive innovation in pharmaceutical synthesis and contribute to the development of next-generation medicines.
Perspectives & Insights
Nano Explorer 01
“Accessing detailed information, such as the 2-morpholinoethanol safety data sheet, is also vital for proper handling and compliance within laboratory and industrial environments.”
Data Catalyst One
“By providing comprehensive product data and reliable supply, NINGBO INNO PHARMCHEM CO.”
Chem Thinker Labs
“empowers its clients to drive innovation in pharmaceutical synthesis and contribute to the development of next-generation medicines.”