The Crucial Role of 2-(Trifluoromethyl)-5-Nitrobenzonitrile in Modern Organic Synthesis
In the intricate world of organic synthesis, the availability of high-quality intermediates is paramount to driving innovation and achieving successful outcomes. Among these essential building blocks, 2-(Trifluoromethyl)-5-Nitrobenzonitrile stands out as a compound of significant utility. As a key component in the synthesis of a diverse range of organic molecules, its precise properties and reliable sourcing are critical for researchers and procurement managers alike.
Understanding the Compound: Properties and Purity
2-(Trifluoromethyl)-5-Nitrobenzonitrile, identified by its CAS number 887350-95-0, is characterized by its appearance as a white to light yellow crystalline powder. Its molecular formula, C8H3F3N2O2, and molecular weight of 216.117 point to a complex structure with significant potential for further chemical transformation. For B2B buyers, the assay of ≥98.0% is a critical specification, guaranteeing the purity required for demanding synthetic applications. This high purity ensures that reactions proceed as intended, minimizing side products and maximizing yields, a key concern for R&D scientists aiming for cost-effective and efficient synthesis.
The Power of Trifluoromethyl and Nitro Groups in Synthesis
The presence of both a trifluoromethyl (-CF₃) group and a nitro (-NO₂) group on the benzonitrile core imbues this molecule with unique reactivity. The trifluoromethyl group is known for its electron-withdrawing capabilities, often enhancing lipophilicity and metabolic stability in resulting molecules, making it a sought-after feature in pharmaceuticals and agrochemicals. The nitro group, on the other hand, is a powerful activating group for nucleophilic aromatic substitution (SNAr) reactions and can be readily reduced to an amine, opening up vast possibilities for further derivatization.
This dual functionality makes 2-(Trifluoromethyl)-5-Nitrobenzonitrile an exceptionally versatile intermediate. Its structure allows for targeted modifications, whether through SNAr reactions on the activated aromatic ring or through reductive transformations of the nitro group. This versatility is precisely why many procurement managers seek out this compound when planning complex synthesis pathways.
Sourcing with Confidence: Manufacturer and Supplier Advantages
For organizations looking to purchase 2-(Trifluoromethyl)-5-Nitrobenzonitrile, partnering with a reliable manufacturer and supplier is crucial. We understand the importance of a stable supply chain, competitive pricing, and consistent product quality. As a dedicated supplier, we offer this vital intermediate with the assurance of high purity and availability, catering to both research-scale and industrial-scale requirements. Whether you are looking to buy for initial research or for large-scale production, understanding the manufacturer's commitment to quality control and efficient logistics is key. For those seeking a quote, working with us ensures you receive comprehensive support from inquiry to delivery.
Applications Across Industries
The utility of 2-(Trifluoromethyl)-5-Nitrobenzonitrile extends across several key industries:
- Pharmaceuticals: It serves as a crucial intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs), particularly where fluorinated aromatic scaffolds are desired for enhanced efficacy and pharmacokinetic properties.
- Agrochemicals: The compound's structure is amenable to the development of new pesticides and herbicides, where fluorine incorporation can improve performance.
- Fine Chemicals: It is a valuable building block for specialty chemicals, contributing unique properties to downstream products.
In conclusion, 2-(Trifluoromethyl)-5-Nitrobenzonitrile is more than just a chemical; it's a gateway to innovation in organic synthesis. By understanding its properties and recognizing the advantages of sourcing from a reliable manufacturer, research and development teams can confidently leverage this powerful intermediate to achieve their synthetic goals.
Perspectives & Insights
Core Pioneer 24
“This high purity ensures that reactions proceed as intended, minimizing side products and maximizing yields, a key concern for R&D scientists aiming for cost-effective and efficient synthesis.”
Silicon Explorer X
“The Power of Trifluoromethyl and Nitro Groups in SynthesisThe presence of both a trifluoromethyl (-CF₃) group and a nitro (-NO₂) group on the benzonitrile core imbues this molecule with unique reactivity.”
Quantum Catalyst AI
“The trifluoromethyl group is known for its electron-withdrawing capabilities, often enhancing lipophilicity and metabolic stability in resulting molecules, making it a sought-after feature in pharmaceuticals and agrochemicals.”