In the intricate world of organic chemistry, particularly within the realm of peptide synthesis, certain reagents stand out for their indispensable roles. Among these, Dicyclohexylcarbodiimide, commonly known as DCC (CAS 538-75-0), holds a prominent position. As a leading supplier of fine chemicals, we understand the critical importance of high-quality DCC for researchers and manufacturers aiming to produce complex peptides efficiently and reliably. This article delves into why DCC is a preferred coupling reagent and how you can procure it from a trusted manufacturer.

The Mechanism of DCC in Peptide Synthesis

Peptide synthesis involves the sequential coupling of amino acids to form a polypeptide chain. This process requires the activation of the carboxyl group of one amino acid to react with the amino group of another. DCC functions as a powerful dehydrating agent, facilitating this crucial coupling reaction. It reacts with the carboxyl group of an N-protected amino acid to form a highly reactive O-acylisourea intermediate. This intermediate is then readily attacked by the free amino group of the next amino acid in the sequence, forming a new peptide bond and releasing dicyclohexylurea (DCU) as a byproduct.

Why Choose DCC? Advantages for Manufacturers and Researchers

The widespread adoption of DCC in peptide synthesis is due to several key advantages:

  • Efficiency: DCC is highly effective in promoting peptide bond formation, often leading to high yields and purity of the desired peptide product.
  • Versatility: It is compatible with a wide range of protecting groups and amino acid derivatives commonly used in solid-phase and solution-phase peptide synthesis.
  • Cost-Effectiveness: As a widely produced chemical, DCC is generally more affordable than some of the newer peptide coupling reagents, making it an attractive option for bulk purchases.
  • Availability: We, as a prominent manufacturer and supplier in China, ensure a consistent and reliable supply of high-purity Dicyclohexylcarbodiimide, meeting the demands of global markets.

Sourcing High-Quality DCC for Your Needs

When you are looking to buy Dicyclohexylcarbodiimide for your peptide synthesis projects, it is crucial to partner with a reputable supplier that guarantees purity and consistency. Our company is committed to providing premium-grade DCC (CAS 538-75-0) that meets stringent quality standards. We understand the importance of reliable raw materials in pharmaceutical and biotechnological applications, and we strive to be your trusted source. Whether you require grams for research or kilograms for industrial production, we are equipped to meet your needs.

By choosing us as your Dicyclohexylcarbodiimide supplier, you are investing in the success of your peptide synthesis endeavors. We offer competitive pricing and efficient delivery from our manufacturing base in China. Contact us today to get a quote for your next purchase and experience the difference that quality and reliability can make.