The Crucial Role of MOPS Sodium Salt in Modern Biological Research
In the dynamic field of biological research, precise control over experimental conditions is paramount. Among the essential tools for scientists, biological buffers play a critical role in maintaining stable pH levels, which directly influences the activity of enzymes, the stability of biomolecules, and the overall success of experiments. One such indispensable buffer is MOPS Sodium Salt (CAS 71119-22-7).
MOPS, or 3-(N-Morpholino)propanesulfonic acid, and its sodium salt form are part of a family of zwitterionic buffers first developed by Good and colleagues. These buffers were meticulously designed to meet stringent criteria for biological research, including a mid-range pKa, high water solubility, and chemical stability. The sodium salt form, MOPS Sodium Salt, specifically offers excellent solubility in water (523 g/l at 20°C), making it convenient to prepare solutions for a variety of applications.
The primary advantage of MOPS Sodium Salt lies in its effective buffering range, typically between pH 6.5 and 8.0, with a pKa of 7.2 at 25°C. This specific pKa value makes it particularly suitable for biological systems that operate within or near physiological pH. Researchers often turn to this buffer for applications requiring stable pH conditions, such as in electrophoresis for separating DNA, RNA, or proteins, and in various biochemical assays including enzyme kinetics and protein purification.
For those looking to buy MOPS Sodium Salt, sourcing from reputable manufacturers and suppliers is key. Companies specializing in laboratory reagents and biochemicals, particularly those based in China, offer high-purity grades (often ≥98%) that are essential for sensitive research. When procuring this chemical, it's important to consider factors like purity, lot-to-lot consistency, and the availability of supporting documentation such as Certificates of Analysis (CoA). Understanding the pricing structures for different quantities, from grams to kilograms, will also aid in efficient budget management for your research projects.
The versatility of MOPS Sodium Salt extends to its use in molecular biology, where maintaining precise pH is critical for nucleic acid manipulation and protein interactions. Its chemical and enzymatic stability ensures that the buffer itself does not interfere with the biological processes being studied. As a go-to buffer in many laboratories, ensuring a reliable supply chain from trusted manufacturers is crucial for uninterrupted research progress.
In conclusion, MOPS Sodium Salt is an indispensable reagent for modern biological and biochemical research. Its well-defined buffering capacity, solubility, and stability make it a cornerstone for numerous experimental techniques. For researchers and procurement managers seeking high-quality MOPS Sodium Salt, exploring options from established suppliers in China provides a strategic advantage in obtaining reliable and cost-effective materials. Consider us your trusted partner for all your biological buffer needs.
Perspectives & Insights
Alpha Spark Labs
“MOPS, or 3-(N-Morpholino)propanesulfonic acid, and its sodium salt form are part of a family of zwitterionic buffers first developed by Good and colleagues.”
Future Pioneer 88
“These buffers were meticulously designed to meet stringent criteria for biological research, including a mid-range pKa, high water solubility, and chemical stability.”
Core Explorer Pro
“The sodium salt form, MOPS Sodium Salt, specifically offers excellent solubility in water (523 g/l at 20°C), making it convenient to prepare solutions for a variety of applications.”