NINGBO INNO PHARMCHEM CO.,LTD. presents a detailed examination of 1-Fluoro-3-chloropropane (CAS 462-38-4), an indispensable chemical intermediate that plays a pivotal role in numerous organic synthesis processes. This article highlights its fundamental properties, synthesis pathways, diverse applications, and the market dynamics influencing its global availability.

Chemical Identity and Physical Characteristics

1-Fluoro-3-chloropropane is an organohalogen compound characterized by the chemical formula C3H6ClF. It appears as a colorless, transparent liquid. Key physical properties include a molecular weight of 96.53 g/mol, a density of approximately 1.0581 g/cm³, and a refractive index of 1.3871. Its boiling point is recorded at 69.68°C. These properties are essential for chemists in designing reaction conditions, optimizing purification steps, and ensuring safe handling. The compound's high purity, typically ≥99.0%, is crucial for its consistent performance as a chemical intermediate, especially in applications requiring stringent quality standards.

Synthetic Pathways and Applications in Industry

The synthesis of 1-fluoro-3-chloropropane involves specific chemical reactions tailored to introduce the fluorine and chlorine atoms onto the propane chain. As a chemical intermediate, its value is immense. It serves as a fundamental building block in the pharmaceutical sector, enabling the synthesis of a wide array of Active Pharmaceutical Ingredients (APIs). The incorporation of fluorine is a common strategy in medicinal chemistry to enhance drug potency, metabolic stability, and lipophilicity. Beyond pharmaceuticals, 1-fluoro-3-chloropropane is utilized in the agrochemical industry for developing effective pesticides and herbicides. It also finds application in the creation of specialty chemicals and advanced materials, where its unique properties contribute to enhanced performance characteristics. The availability of this compound from reliable manufacturers allows for its widespread use in research and industrial production.

Market Significance and Sourcing Strategies

China has established itself as a dominant force in the global chemical manufacturing landscape, particularly for fine chemicals and intermediates like 1-fluoro-3-chloropropane. Sourcing from Chinese suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., offers distinct advantages, including competitive pricing, scalability, and consistent quality. Adhering to proper storage and handling protocols is vital; the compound should be stored in cool, well-ventilated areas, away from heat sources and incompatible materials. Understanding the 1-fluoro-3-chloropropane properties and safety guidelines is essential for all users.

Conclusion

1-Fluoro-3-chloropropane is a critical component in the toolkit of modern organic chemists. Its well-defined properties and versatile reactivity make it a go-to intermediate for innovation in pharmaceuticals, agrochemicals, and specialty chemicals. By ensuring reliable sourcing and adhering to safety best practices, industries can continue to leverage the full potential of this essential chemical.