The Indispensable Role of 2-Bromopyridine in Modern Organic Synthesis
NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight the significance of 2-Bromopyridine (CAS 109-04-6) in the field of organic chemistry. This compound, characterized by its pyridine ring substituted with a bromine atom at the 2-position, serves as a cornerstone for numerous synthetic pathways. Its primary utility lies in its ability to participate in various cross-coupling reactions, which are fundamental for constructing complex organic molecules. Specifically, its role in C-N bond formation is critical, allowing chemists to efficiently link nitrogen-containing fragments to carbon frameworks. This capability is especially important in the development of pharmaceuticals and agrochemicals, where precise molecular engineering is paramount.
One of the most celebrated reactions involving 2-Bromopyridine is the Negishi cross-coupling. This palladium-catalyzed reaction allows for the formation of carbon-carbon bonds between organozinc reagents and organic halides or pseudohalides. In the case of 2-Bromopyridine, it enables the introduction of a 2-pyridyl moiety into a variety of substrates, opening doors to novel molecular architectures. The ability to reliably perform such transformations underscores the value of having a high-purity supply of 2-Bromopyridine. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our clients receive material that meets stringent quality standards, essential for reproducible and successful experimental outcomes. The availability of 2-Bromopyridine for purchase from NINGBO INNO PHARMCHEM CO.,LTD. is a testament to our commitment to supporting cutting-edge research and development.
Beyond cross-coupling, 2-Bromopyridine is also a precursor to 2-lithiopyridine. This organolithium reagent is exceptionally reactive and serves as a powerful nucleophile in various synthetic procedures. The preparation of 2-lithiopyridine from 2-Bromopyridine is a common strategy for introducing the pyridyl group into diverse organic compounds. This versatility makes 2-Bromopyridine an indispensable tool for medicinal chemists and material scientists alike. Whether the goal is to synthesize a new drug candidate, develop advanced materials, or explore novel catalytic systems, the reliable supply and high quality of 2-Bromopyridine from NINGBO INNO PHARMCHEM CO.,LTD. is a key enabler. We are dedicated to providing the chemical building blocks that drive innovation in science and industry, making the purchase of essential intermediates like 2-Bromopyridine a seamless process for our partners.
Perspectives & Insights
Logic Thinker AI
“is a testament to our commitment to supporting cutting-edge research and development.”
Molecule Spark 2025
“This organolithium reagent is exceptionally reactive and serves as a powerful nucleophile in various synthetic procedures.”
Alpha Pioneer 01
“The preparation of 2-lithiopyridine from 2-Bromopyridine is a common strategy for introducing the pyridyl group into diverse organic compounds.”