NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing advanced chemical solutions, and among our most valuable offerings is Diisopropylcarbodiimide (DIC). This versatile compound, identified by its CAS number 693-13-0, has become indispensable in contemporary organic synthesis, particularly within the demanding field of peptide synthesis.

Peptide synthesis, the process of creating peptide chains from individual amino acids, requires precise control over bond formation and careful management of by-products. DIC excels in this domain as a highly effective coupling reagent. Unlike older solid carbodiimides, DIC's liquid form at room temperature makes it significantly easier to handle and measure accurately. This improved usability translates directly into more efficient workflows and reduced operational errors in research and manufacturing settings.

One of the critical advantages of using DIC in peptide synthesis is the nature of its by-product. When DIC facilitates the formation of an amide bond between amino acids, it converts into N,N'-diisopropylurea. This urea derivative is soluble in most common organic solvents, such as dichloromethane or acetonitrile. This solubility is a major advantage over the urea by-product from dicyclohexylcarbodiimide (DCC), which is notoriously insoluble and can be difficult to remove, often complicating the purification of the target peptide. The ease of removing the soluble diisopropylurea by-product streamlines the downstream processing, saving valuable time and resources in the production of therapeutic peptides and other biomolecules.

The application of DIC extends beyond just coupling. It acts as a dehydrating agent, promoting reactions that involve the removal of water molecules. This dehydrating capability is crucial in many organic transformations, including the synthesis of esters, anhydrides, and other functional groups. Researchers often buy DIC for its reliability in driving these reactions to completion with high yields.

For those looking to purchase Diisopropylcarbodiimide, NINGBO INNO PHARMCHEM CO.,LTD. offers high-purity DIC, ensuring consistency and performance in your synthetic endeavors. Whether you are involved in the synthesis of complex pharmaceutical intermediates, novel drug candidates, or specialized biochemicals, incorporating DIC into your synthetic strategy can lead to significant improvements in efficiency and product quality. The ability to purchase this key reagent from a trusted supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures that your research and production pipelines remain robust and productive.

In summary, the strategic use of Diisopropylcarbodiimide in modern chemical synthesis, especially for peptide coupling and as a dehydrating agent, highlights its importance. Its practical advantages in handling and purification make it a preferred choice for chemists worldwide. NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply this essential reagent, supporting advancements in medicine and science.