In the intricate world of organic chemistry and drug development, the precise manipulation of amino acids is paramount. N6-Cbz-L-Lysine, identified by its CAS number 1155-64-2, stands out as a crucial intermediate and protecting group. For procurement managers and R&D scientists seeking high-quality materials, understanding its role and sourcing reliable suppliers is key. This article delves into the significance of N6-Cbz-L-Lysine, particularly for those looking to buy from a reputable China manufacturer.

What is N6-Cbz-L-Lysine?

N6-Cbz-L-Lysine is a derivative of the essential amino acid L-lysine. The 'Cbz' or 'Z' group (carbobenzyloxy) serves as a protecting group for the epsilon-amino group of lysine. This protection is vital in peptide synthesis, preventing unwanted reactions at that site while other parts of the molecule are modified. Its chemical formula is C14H20N2O4, with a molecular weight of approximately 280.32 g/mol. It typically presents as a white to off-white crystalline powder, a characteristic that aids in its handling and quality assessment.

The Importance in Peptide Synthesis

Peptide synthesis is a cornerstone of modern biochemistry and pharmaceutical research. It involves the sequential coupling of amino acids to form peptide chains. Lysine, with its two amino groups (one alpha and one epsilon), presents a challenge. If both are unprotected, it can lead to polymerization or side reactions. This is where N6-Cbz-L-Lysine shines. By selectively protecting the epsilon-amino group, it allows for controlled elongation of the peptide chain at the alpha-amino group. Researchers and manufacturers often seek to buy N6-Cbz-L-Lysine with high purity, typically above 98%, to ensure the integrity and yield of their synthesized peptides. The availability of this compound from reliable suppliers in China is a significant advantage for global R&D efforts.

Applications in Drug Development

Beyond peptide synthesis, N6-Cbz-L-Lysine acts as a valuable building block and intermediate in the synthesis of various pharmaceutical compounds. Its protected lysine structure can be incorporated into more complex molecules, contributing to the development of new therapeutics. For companies involved in drug discovery, sourcing this compound from reputable manufacturers is essential for ensuring the quality and consistency of their active pharmaceutical ingredients (APIs). The price of N6-Cbz-L-Lysine can vary based on purity and quantity, making it important to secure a stable supply chain with competitive pricing.

Sourcing N6-Cbz-L-Lysine: Manufacturer Insights

When looking to purchase N6-Cbz-L-Lysine, partnering with a manufacturer that can guarantee quality and consistent supply is critical. Many global pharmaceutical and research institutions rely on China-based manufacturers for this and other fine chemical intermediates. These manufacturers often offer competitive pricing and can handle bulk orders, making them ideal for large-scale production needs. When inquiring about N6-Cbz-L-Lysine, pay attention to specifications like purity (e.g., ≥98.0%), appearance, and packaging (commonly 25kg drums). The EINECS number (214-585-7) and CAS number (1155-64-2) are essential identifiers to ensure you are sourcing the correct material.

In conclusion, N6-Cbz-L-Lysine is an indispensable tool for chemists and pharmacologists. Its role in peptide synthesis and its utility as a pharmaceutical intermediate make it a high-demand chemical. For those seeking to buy this critical compound, engaging with established manufacturers and suppliers, especially those in China, can provide access to high-purity materials at favorable prices, thereby supporting innovation and efficient production.