Understanding the precise function of chemical reagents is key to optimizing synthetic pathways. 2-Chloro-4,6-dimethoxy-1,3,5-triazine (CDMT), with CAS number 3140-73-6, is a highly effective condensation reagent, widely employed in organic synthesis for its role in facilitating amide and peptide bond formation. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer and supplier, is dedicated to providing B2B clients with access to this important chemical and the knowledge to utilize it effectively.

The mechanism of CDMT involves the activation of a carboxylic acid group. In the presence of a base, such as N-methylmorpholine (NMM), CDMT reacts with the carboxylate anion to form a highly reactive O-acyltriazine intermediate. This intermediate is then readily attacked by a nucleophile, typically an amine, leading to the formation of a stable amide bond and the release of a less reactive triazine byproduct. This process is significantly more efficient and controlled compared to some older methods, making CDMT a preferred choice when you need to buy reliable coupling reagents.

The efficiency of CDMT is particularly notable in peptide synthesis, where it enables the coupling of amino acids with high yields and minimal racemization. This is essential for producing biologically active peptides and complex protein structures. Our commitment as a manufacturer in China means we supply CDMT with a guaranteed purity of ≥98.0% (HPLC), ensuring predictable and reproducible results in your experiments and production runs. As a trusted supplier, we aim to offer this high-quality product at the best possible price.

Furthermore, CDMT's versatility extends to other condensation reactions, including esterification and the synthesis of various heterocycles. Its ability to activate a broad range of substrates, including those that are sterically hindered, makes it an invaluable tool for chemists tackling challenging synthetic problems. When your project demands efficient amide bond formation or reliable peptide coupling, consider purchasing from a manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. that prioritizes quality and consistent supply.

We encourage researchers and industry professionals to explore the scientific advantages of 2-Chloro-4,6-dimethoxy-1,3,5-triazine. Partner with NINGBO INNO PHARMCHEM CO.,LTD. for your supply needs and benefit from our expertise as a leading chemical manufacturer. Contact us to request a quotation or sample, and discover how our high-quality CDMT can enhance your synthesis projects.