The chemical industry thrives on the development and utilization of specialized intermediates that enable the synthesis of complex and high-value products. Among these, organoboron compounds, particularly boronic acids, hold a prominent position due to their remarkable versatility in carbon-carbon bond formation. CAS 874289-44-8, scientifically known as 5-(cyclohexylcarbamoyl)-2-fluorobenzeneboronic acid, is a prime example of such a critical intermediate.

This compound features a unique molecular architecture combining a benzene ring substituted with a fluorine atom at the ortho position to a boronic acid group, and a cyclohexylcarbamoyl substituent at the para position. This specific arrangement of functional groups imparts distinct chemical properties that are highly desirable in advanced synthesis. The boronic acid moiety (B(OH)2) is well-known for its participation in palladium-catalyzed cross-coupling reactions, most notably the Suzuki-Miyaura reaction, which is a workhorse in both academic research and industrial production for creating biaryl compounds and other complex organic structures.

The presence of the fluorine atom is particularly significant. Fluorine, being highly electronegative, can influence the electronic distribution within the molecule, thereby affecting the reactivity of the boronic acid group and the properties of the resultant coupled products. In medicinal chemistry, fluorination is a common strategy to enhance metabolic stability, increase lipophilicity, and improve the binding affinity of drug molecules. Therefore, intermediates like CAS 874289-44-8 are invaluable for pharmaceutical development.

The cyclohexylcarbamoyl group also plays a crucial role. It contributes to the overall steric profile of the molecule and can influence solubility and intermolecular interactions. This makes 5-(cyclohexylcarbamoyl)-2-fluorobenzeneboronic acid a versatile building block, suitable for synthesizing a wide range of compounds with tailored physical and biological properties. Researchers seeking to buy 5-(cyclohexylcarbamoyl)-2-fluorobenzeneboronic acid often do so for its specific advantages in constructing complex scaffolds.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated organic synthesis boronic acid supplier, committed to providing researchers and manufacturers with high-quality intermediates. We understand the importance of the CAS 874289-44-8 chemical properties, including its typical purity of 98% and a melting point of 164°C, for successful synthesis. As a reliable provider of pharmaceutical building blocks boronic acid, we ensure that our clients have access to the critical materials needed for their projects. Whether for pharmaceutical R&D or the creation of novel materials, this compound serves as a potent tool in the chemist's arsenal.

The strategic use of intermediates like 5-(cyclohexylcarbamoyl)-2-fluorobenzeneboronic acid underscores the continuous innovation within the chemical industry. By providing access to such specialized fluorinated benzeneboronic acid intermediate compounds, NINGBO INNO PHARMCHEM CO.,LTD. facilitates progress in creating new medicines, advanced materials, and innovative chemical processes. Trust us as your partner for all your organic synthesis needs.