Fine chemicals are the backbone of many advanced industries, providing the essential molecular components for everything from pharmaceuticals to advanced materials. Among these, 3-bromoacetophenone (CAS 2142-63-4), also known as m-bromoacetophenone or 1-(3-bromophenyl)ethanone, is a particularly valuable compound. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted supplier of this critical fine chemical, recognizing its significant role in various synthetic processes and applications.

The synthesis of 3-bromoacetophenone typically involves the electrophilic aromatic substitution of acetophenone. Common methods include the direct bromination of acetophenone using bromine in the presence of a Lewis acid catalyst, or through the reaction of 3-bromobenzoyl chloride with methylmagnesium bromide. Alternatively, it can be prepared via Friedel-Crafts acylation of bromobenzene. The specific synthetic route chosen often depends on factors like desired purity, yield, cost-effectiveness, and available reagents. NINGBO INNO PHARMCHEM CO.,LTD. employs robust synthesis and purification techniques to ensure a high-purity product (typically 98%) essential for its intended applications.

The utility of 3-bromoacetophenone spans several sectors due to its unique chemical structure. In the pharmaceutical industry, it serves as a crucial intermediate for the synthesis of various APIs. The aryl bromide moiety allows for facile functionalization through palladium-catalyzed cross-coupling reactions, enabling the construction of complex drug molecules. The ketone group offers further reactivity, supporting the introduction of diverse functional groups or the formation of new ring systems. Beyond pharmaceuticals, its applications extend to the cosmetic industry, where it may be used in specialized formulations.

Understanding the chemical properties of 1-(3-bromophenyl)ethanone is key to leveraging its full potential. It is generally observed as a white powder, soluble in common organic solvents such as acetone and benzene, and possesses a defined density and boiling point, facilitating its handling and use in laboratory and industrial settings. The versatility of 3-bromoacetophenone is further highlighted by the broad range of CAS 2142-63-4 chemical uses, which include its role as a building block in the synthesis of organic electronic materials, agrochemicals, and various research chemicals. Its meta-substitution pattern offers distinct electronic properties compared to ortho or para isomers, making it a unique tool for regioselective synthesis.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality fine chemicals that drive innovation across industries. Our expertise in the synthesis and supply of compounds like 3-bromoacetophenone ensures that researchers and manufacturers have access to the reliable materials they need. Whether you require this compound for pharmaceutical synthesis, cosmetic formulation, or advanced organic research, NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner. We are dedicated to supporting your projects with products that meet the highest standards of purity and efficacy.