Thiophene-2-ethylamine: Your Go-To Building Block for Pharmaceutical Synthesis
For researchers and procurement managers in the pharmaceutical sector, sourcing high-quality chemical intermediates is paramount to successful drug development. Thiophene-2-ethylamine, identified by its CAS number 30433-91-1, stands out as a particularly versatile and valuable building block. This heterocyclic amine offers a unique combination of a thiophene ring and an ethylamine side chain, providing distinct chemical reactivity that is highly sought after in the synthesis of a wide range of bioactive molecules.
The utility of Thiophene-2-ethylamine spans various therapeutic areas. Its structural features make it an excellent starting material for compounds exhibiting potential anti-cancer, anti-inflammatory, and antiviral properties. For instance, derivatives of Thiophene-2-ethylamine have been explored in the context of developing geldanamycin derivatives, which target heat shock protein 90 (Hsp90) and show promise in treating certain cancers. The ability to functionalize this molecule allows medicinal chemists to fine-tune pharmacological profiles, optimize target binding, and improve pharmacokinetic properties of novel drug candidates.
When considering where to purchase Thiophene-2-ethylamine, buyers often look for reliability, purity, and competitive pricing. Manufacturers in China have emerged as significant suppliers, offering this compound with high purity levels (often exceeding 97% or 98%) and in various quantities suitable for both R&D and larger-scale production. Procurement managers can find numerous suppliers by searching for 'buy Thiophene-2-ethylamine CAS 30433-91-1' or 'Thiophene-2-ethylamine supplier in China.' Engaging with a reputable Chinese manufacturer ensures a stable supply chain and often provides cost advantages compared to other regions.
The chemical synthesis involving Thiophene-2-ethylamine leverages its amine group for nucleophilic reactions and its thiophene ring for electrophilic aromatic substitutions or cross-coupling reactions. This dual reactivity allows for complex molecular architectures to be built efficiently. For example, it can be reacted with isothiocyanatoketones to form pyrimidine derivatives or with aroyl S-methylisothioureas to create acylguanidines, both important classes of compounds in medicinal chemistry. Furthermore, its role as an intermediate in synthesizing anti-platelet drugs like clopidogrel analogs highlights its significance in cardiovascular medicine.
For R&D scientists and procurement specialists aiming to advance their pharmaceutical projects, understanding the availability and specifications of key intermediates like Thiophene-2-ethylamine is crucial. By partnering with a reliable manufacturer or supplier, you can secure this essential chemical building block, paving the way for accelerated discovery and development of innovative therapeutics. Make sure to inquire about pricing and request samples from trusted Chinese suppliers to ensure the quality and suitability for your specific pharmaceutical synthesis needs.
Perspectives & Insights
Agile Reader One
“For R&D scientists and procurement specialists aiming to advance their pharmaceutical projects, understanding the availability and specifications of key intermediates like Thiophene-2-ethylamine is crucial.”
Logic Vision Labs
“By partnering with a reliable manufacturer or supplier, you can secure this essential chemical building block, paving the way for accelerated discovery and development of innovative therapeutics.”
Molecule Origin 88
“Make sure to inquire about pricing and request samples from trusted Chinese suppliers to ensure the quality and suitability for your specific pharmaceutical synthesis needs.”