For chemists engaged in the synthesis of complex organic molecules, the introduction of a cyano group (-CN) is a frequently encountered and highly valuable transformation. Traditionally, this has involved the use of hydrogen cyanide (HCN), a notoriously toxic and volatile gas. However, the advent of Trimethylsilyl Cyanide (TMSCN), identified by CAS number 7677-24-9, has revolutionized this process, offering a significantly safer and more convenient alternative for researchers and industrial manufacturers alike.

As a dedicated supplier and manufacturer of specialty chemicals, we recognize the importance of providing reagents that enhance both safety and efficiency in the laboratory and production floor. TMSCN, a clear, colorless to pale yellow liquid, is a prime example of such an advancement. Its primary function is as a source of the cyanide anion, readily reacting with various electrophilic centers. Its applications are widespread, particularly in the cyanosilylation of carbonyl compounds (aldehydes and ketones) to form cyanohydrin trimethylsilyl ethers, which are pivotal intermediates in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals.

Why TMSCN is the Preferred Choice for Cyanation:

  • Superior Safety: The handling of hydrogen cyanide poses significant risks. TMSCN, being a liquid with a lower vapor pressure, dramatically reduces these risks, making it a much safer option for procurement managers and laboratory personnel. When you buy TMSCN, you invest in a safer synthetic process.
  • Broad Reactivity Spectrum: Beyond carbonyls, TMSCN is instrumental in Strecker-type reactions to form alpha-aminonitriles and can be utilized in Michael additions and other transformations, demonstrating its versatility for diverse synthetic challenges faced by R&D scientists.
  • Facilitating Complex Synthesis: For companies involved in advanced organic synthesis and chemical manufacturing, TMSCN is a key reagent. Its controlled reactivity allows for precise introduction of the cyano group, leading to higher yields and purer products, which is critical for downstream applications.

Sourcing and Partnership with a Trusted Manufacturer

Finding a reliable supplier for essential reagents like TMSCN is crucial for maintaining consistent production and research timelines. We are a prominent manufacturer and supplier of Trimethylsilyl Cyanide in China, committed to delivering products of the highest purity. Our streamlined procurement process allows you to easily request a quote and purchase TMSCN, whether for laboratory research or large-scale industrial manufacturing. We understand the needs of procurement managers who seek cost-effective solutions without compromising on quality or safety.

Embrace a safer and more efficient approach to cyanation. Partner with us to procure your Trimethylsilyl Cyanide requirements. Contact our sales team today to discuss your needs and discover how our high-quality TMSCN can benefit your chemical synthesis projects.