For professionals in the chemical and pharmaceutical sectors, a deep understanding of key chemical intermediates is crucial for effective product development and manufacturing. 1,2-Dibromobenzene (CAS 583-53-9) is a compound that warrants close attention due to its significant utility. This article provides an overview of its properties, primary applications, and essential considerations for procurement from reliable manufacturers.

1,2-Dibromobenzene, also known as o-dibromobenzene, is an aromatic hydrocarbon characterized by the presence of two bromine atoms attached to adjacent carbon atoms on a benzene ring. Typically appearing as a clear to light yellow liquid, it possesses a molecular formula of C6H4Br2 and a molecular weight of approximately 235.9 g/mol. Its physical properties, such as a boiling point of around 224°C and a melting point between 4-6°C (though some sources cite higher values), are important for handling and reaction design. The density of 1,2-Dibromobenzene is approximately 1.956 g/mL. Its purity, often specified as ≥99.0% or ≥99.5%, is a critical factor for its successful application.

The primary applications of 1,2-Dibromobenzene are rooted in its reactivity as an aryl halide. It serves as a versatile intermediate in a wide range of organic synthesis reactions. This includes its use in the preparation of organometallic reagents and its participation in various cross-coupling methodologies, which are fundamental for building complex molecular structures found in pharmaceuticals, agrochemicals, and materials science. Furthermore, 1,2-Dibromobenzene acts as a precursor for certain dyes and pigments, contributing to the color and performance properties of these essential industrial products. When considering purchase options, understanding these application areas helps in specifying the required purity and quantity.

Procuring 1,2-Dibromobenzene requires diligence in selecting a trustworthy manufacturer or supplier. Buyers should prioritize suppliers who can consistently deliver material meeting the specified purity standards, often supported by detailed Certificates of Analysis. Competitive pricing is also a key consideration, especially for bulk orders. Many international buyers look towards established chemical manufacturing hubs like China for cost-effective solutions. For instance, companies like NINGBO INNO PHARMCHEM offer 1,2-Dibromobenzene with guaranteed high purity and competitive pricing, often coupled with robust logistical support for export. Engaging directly with such manufacturers can streamline the procurement process and ensure supply chain reliability.

In conclusion, 1,2-Dibromobenzene is a foundational chemical intermediate essential for numerous synthetic pathways and industrial applications. By understanding its properties, applications, and procurement best practices, procurement managers and R&D scientists can make informed decisions. Partnering with reputable manufacturers who prioritize quality and offer competitive pricing is key to successfully integrating this compound into your operations.