For chemists engaged in organic synthesis, a deep understanding of chemical intermediates is fundamental to innovation and efficient production. 1-[3-(Dimethylamino)propyl]piperazine, known by its CAS number 877-96-3, is a chemical compound that warrants attention for its structural features and potential applications. This article aims to provide chemists with essential information about its properties, synthetic utility, and guidance on sourcing it from reliable manufacturers.

The chemical profile of 1-[3-(Dimethylamino)propyl]piperazine is defined by its molecular formula, C9H21N3, and a molecular weight of 171.28. It is commonly described as a clear, light yellow liquid. Standard physical properties include a boiling point of approximately 77°C and a density of about 0.911 g/cm³. A critical specification for its use in synthesis is its purity, which typically exceeds 95%. This level of purity ensures that it can be effectively incorporated into complex reaction schemes without introducing undesirable side products that could complicate purification or affect the yield of the target molecule.

The primary role of 1-[3-(Dimethylamino)propyl]piperazine in chemical synthesis stems from its bifunctional nature. The piperazine ring provides a readily functionalizable cyclic diamine structure, while the dimethylamino propyl side chain introduces a tertiary amine group. This combination makes it a versatile building block for creating a wide array of organic molecules. Chemists may utilize it in reactions such as alkylations, acylations, and as a nucleophile in various coupling reactions. Its ability to act as a base or a chelating agent can also be exploited in certain synthetic strategies.

When planning to buy 1-[3-(Dimethylamino)propyl]piperazine for your laboratory or pilot-scale synthesis, it is essential to partner with a reputable chemical manufacturer or supplier. Factors such as consistent quality, availability, and technical support are crucial. Manufacturers often provide detailed technical data sheets and Certificates of Analysis (COAs) that confirm the compound's specifications, including its CAS number and purity. For chemists in research and development, having a reliable source that can also offer custom synthesis services for related derivatives can be highly beneficial.

The successful synthesis of target molecules often depends on the quality of the starting materials. Therefore, selecting a supplier that guarantees the purity and consistency of 1-[3-(Dimethylamino)propyl]piperazine is paramount. While many suppliers offer this compound, it is advisable to compare their offerings, particularly regarding price and delivery times, especially if you intend to buy in larger quantities. Many suppliers based in China offer competitive pricing for this intermediate.

In summary, 1-[3-(Dimethylamino)propyl]piperazine is a valuable and versatile intermediate for organic chemists. By understanding its properties and applications, and by carefully selecting a trustworthy manufacturer, you can ensure the quality and efficiency of your synthetic endeavors. We recommend reaching out to established chemical suppliers to inquire about pricing and availability for your upcoming projects.