Understanding 1-Bromo-3-iodobenzene (CAS 591-18-4): Properties and Synthesis Uses
1-Bromo-3-iodobenzene, bearing the CAS number 591-18-4, is a compound of significant interest in the field of organic chemistry. Appearing as a clear to light yellow liquid, its purity typically meets or exceeds 99%, making it a reliable choice for various synthetic applications. This halogenated aromatic hydrocarbon is characterized by its specific substitution pattern, which imparts unique reactivity and makes it a valuable intermediate. For chemists looking to understand its fundamental characteristics and synthetic utility, a closer look at its properties and applications is warranted.
Physically, 1-Bromo-3-iodobenzene has a melting point of approximately -9.3 °C and a boiling point of 120 °C at 18 mm Hg. Its density is around 2.219 g/mL at 25°C. Importantly, it is known to be light-sensitive, requiring storage in a cool, dark place to maintain its stability. Chemically, it is incompatible with strong oxidizing agents, bases, and acids, which can lead to undesirable reactions. These properties guide its handling and storage protocols, ensuring its effectiveness in downstream processes.
The primary application of 1-Bromo-3-iodobenzene is as an organic synthesis intermediate. Its structure, featuring both a bromine and an iodine atom at meta positions on the benzene ring, allows for regioselective functionalization. This is particularly useful in sequential cross-coupling reactions, where different halogens can be activated under specific catalytic conditions. This versatility enables the synthesis of complex molecules that are vital for pharmaceutical research, material science, and the development of fine chemicals. For instance, it serves as a starting material in the preparation of specialized fluorinated compounds and biaryl systems.
For professionals in the chemical industry, sourcing high-quality 1-Bromo-3-iodobenzene is essential. Companies looking to buy 1-Bromo-3-iodobenzene often turn to specialized CAS 591-18-4 chemical suppliers. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer in China, provides this intermediate with consistent quality, supporting diverse research and industrial needs. Their expertise ensures that the compound meets the necessary purity and reactivity standards for demanding synthetic procedures.
In conclusion, 1-Bromo-3-iodobenzene (CAS 591-18-4) is a fundamental organic synthesis intermediate whose properties make it highly valuable. Its applications span from pharmaceutical development to material science, highlighting its versatility. Understanding its characteristics and reliable sourcing channels, such as NINGBO INNO PHARMCHEM CO.,LTD., is key for successful chemical synthesis.
Physically, 1-Bromo-3-iodobenzene has a melting point of approximately -9.3 °C and a boiling point of 120 °C at 18 mm Hg. Its density is around 2.219 g/mL at 25°C. Importantly, it is known to be light-sensitive, requiring storage in a cool, dark place to maintain its stability. Chemically, it is incompatible with strong oxidizing agents, bases, and acids, which can lead to undesirable reactions. These properties guide its handling and storage protocols, ensuring its effectiveness in downstream processes.
The primary application of 1-Bromo-3-iodobenzene is as an organic synthesis intermediate. Its structure, featuring both a bromine and an iodine atom at meta positions on the benzene ring, allows for regioselective functionalization. This is particularly useful in sequential cross-coupling reactions, where different halogens can be activated under specific catalytic conditions. This versatility enables the synthesis of complex molecules that are vital for pharmaceutical research, material science, and the development of fine chemicals. For instance, it serves as a starting material in the preparation of specialized fluorinated compounds and biaryl systems.
For professionals in the chemical industry, sourcing high-quality 1-Bromo-3-iodobenzene is essential. Companies looking to buy 1-Bromo-3-iodobenzene often turn to specialized CAS 591-18-4 chemical suppliers. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer in China, provides this intermediate with consistent quality, supporting diverse research and industrial needs. Their expertise ensures that the compound meets the necessary purity and reactivity standards for demanding synthetic procedures.
In conclusion, 1-Bromo-3-iodobenzene (CAS 591-18-4) is a fundamental organic synthesis intermediate whose properties make it highly valuable. Its applications span from pharmaceutical development to material science, highlighting its versatility. Understanding its characteristics and reliable sourcing channels, such as NINGBO INNO PHARMCHEM CO.,LTD., is key for successful chemical synthesis.
Perspectives & Insights
Quantum Pioneer 24
“The primary application of 1-Bromo-3-iodobenzene is as an organic synthesis intermediate.”
Bio Explorer X
“Its structure, featuring both a bromine and an iodine atom at meta positions on the benzene ring, allows for regioselective functionalization.”
Nano Catalyst AI
“This is particularly useful in sequential cross-coupling reactions, where different halogens can be activated under specific catalytic conditions.”