Understanding 1-Fluoro-2-iodobenzene: Properties, Reactions, and Sourcing in China
1-Fluoro-2-iodobenzene (CAS 348-52-7) is a compound that captures the interest of organic chemists, researchers, and procurement specialists across various industries due to its distinctive chemical structure and reactivity. This halogenated aromatic hydrocarbon, characterized by a fluorine atom and an iodine atom positioned ortho to each other on a benzene ring, serves as a foundational element in numerous synthetic pathways. Understanding its fundamental properties, key reactions, and reliable sourcing channels is crucial for leveraging its full potential.
Physically, 1-Fluoro-2-iodobenzene is typically described as a clear, light yellow liquid. Its melting point is approximately -41 to -40 °C, and its boiling point is around 188-189 °C. The density is approximately 1.903 g/mL at 25 °C, and its refractive index is 1.59. Importantly, it is sensitive to light, necessitating appropriate storage conditions, such as in dark, inert environments, to maintain its integrity and reactivity. The compound is categorized as an irritant and is harmful if swallowed, underscoring the need for proper handling and safety precautions in laboratory and industrial settings. Professionals often research the 1-fluoro-2-iodobenzene chemical properties and applications to ensure safe and effective utilization.
The chemical reactivity of 1-Fluoro-2-iodobenzene is primarily dictated by the presence of the iodine atom, which is a good leaving group, and the fluorine atom, which influences the electronic distribution of the aromatic ring. This makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, most notably the Suzuki-Miyaura coupling. In these reactions, it readily reacts with organoboron compounds to form new carbon-carbon bonds, allowing for the synthesis of more complex aromatic structures. The efficiency of these reactions is critical for pharmaceutical synthesis, agrochemical development, and material science innovations. Consequently, many researchers and manufacturers seek to buy 1-fluoro-2-iodobenzene CAS 348-52-7 manufacturer for high-purity material.
For industrial procurement, sourcing from reliable manufacturers is paramount. Many organizations specifically look for a supplier of 2-fluoroiodobenzene for Suzuki reaction to ensure consistent quality and supply chain stability. When considering international sourcing, particularly from China, the question of where to purchase high purity 1-fluoro-2-iodobenzene in China frequently arises. Establishing a partnership with a reputable 1-fluoro-2-iodobenzene manufacturer can provide a significant competitive advantage by ensuring both quality and a competitive 1-fluoro-2-iodobenzene for pharmaceutical synthesis price or for other industrial applications.
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Core Pioneer 24
“We are committed to being a leading provider of high-purity 1-Fluoro-2-iodobenzene.”
Silicon Explorer X
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Quantum Catalyst AI
“We encourage you to contact us to discuss your requirements and to learn more about our product offerings.”