For professionals in the chemical industry, from procurement managers to R&D scientists, a thorough understanding of key chemical intermediates is essential. 2-Iodothiophene (CAS: 3437-95-4) is one such compound, a fundamental building block with significant utility across various sectors. This article aims to provide a detailed overview of its properties, applications, synthesis, and how to source it effectively.

Key Properties of 2-Iodothiophene

2-Iodothiophene is an organoiodine compound derived from thiophene. Its physical and chemical properties are critical for its application:

  • Appearance: Typically a yellow to brown to dark green clear liquid.
  • Purity: Commonly available in grades of 97% or higher, with 98% purity being standard for many applications.
  • Molecular Formula: C4H3IS
  • Molecular Weight: 210.04 g/mol
  • CAS Number: 3437-95-4
  • Melting Point: -40 °C
  • Boiling Point: Around 181-185 °C (with variations depending on pressure).
  • Density: Approximately 1.902 g/cm³.
  • Refractive Index: 1.651-1.653.

These properties make it a manageable and reactive intermediate for diverse chemical transformations.

Applications Driving Demand

The versatility of 2-Iodothiophene stems from its ability to participate in a wide array of organic reactions. Its primary applications include:

  • Organic Synthesis: It serves as a precursor in the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and specialty materials.
  • Material Science: Essential for creating organic semiconductors, conductive polymers, and components for electronic devices like OLEDs and OPVs.
  • Pharmaceutical Development: Used as an intermediate in the synthesis of drug candidates containing the thiophene moiety.
  • Research and Development: A common reagent in academic and industrial laboratories for exploring new synthetic pathways and novel compounds.

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Synthesis Considerations

Several synthesis methods exist, including the direct iodination of thiophene. Reputable manufacturers ensure high purity through controlled reaction conditions and purification techniques. Understanding the synthesis process helps appreciate the quality and reliability of the product.

Finding a Reliable Supplier

For businesses needing to purchase 2-Iodothiophene, identifying a trustworthy manufacturer is paramount. Look for suppliers who offer:

  • High Purity Products: With detailed specifications and Certificates of Analysis (CoA).
  • Competitive Pricing: Especially for bulk orders.
  • Reliable Supply Chain: Ensuring consistent availability.
  • Technical Support and Documentation: Including Safety Data Sheets (SDS).

As a leading manufacturer and supplier of fine chemicals, we are committed to providing high-quality 2-Iodothiophene. We invite you to contact us for a quote, to learn more about our product, or to request a sample. Secure your supply of this essential intermediate from a trusted source.