3-Chloropropyne, also widely recognized as Propargyl Chloride, bearing the CAS number 624-65-7, is a vital organic compound with distinct chemical characteristics that lend themselves to a variety of industrial applications. Understanding its properties, synthesis, and safe handling is crucial for effective utilization. NINGBO INNO PHARMCHEM CO.,LTD., a leading chemical manufacturer in China, offers insights into this important intermediate.

Physically, 3-Chloropropyne is typically described as a colorless transparent liquid. Its molecular formula is C3H3Cl, with a molecular weight of approximately 74.51 g/mol. Key properties include a boiling point around 57.0 °C at standard pressure and a flash point of approximately 18.9 °C, indicating its flammability. The compound is noted for its reactivity, particularly due to the presence of the propargyl group (a terminal alkyne) and the chlorine atom, making it an excellent propargylating agent in organic synthesis.

The synthesis of 3-Chloropropyne often involves processes starting from precursors like propargyl alcohol or propyne. While specific manufacturing routes can vary, the goal is always to achieve high purity. For instance, purification might involve fractional distillation. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. adhere to stringent quality standards, often achieving an assay of ≥99% to meet the demands of sensitive applications such as pharmaceutical synthesis and agrochemical production.

Safety considerations are paramount when working with 3-Chloropropyne. Due to its flammability and toxicity, proper storage and handling procedures must be followed. It is typically stored in cool, well-ventilated areas, with containers kept tightly closed. Users should always consult the Material Safety Data Sheet (MSDS) for detailed information on hazards, personal protective equipment (PPE), and emergency procedures. This is a standard practice for any chemical intermediate, especially those utilized in complex synthesis pathways.

The applications of 3-Chloropropyne are broad, serving as a crucial intermediate in the synthesis of pharmaceuticals and pesticides. It is also valued as a metal corrosion inhibitor. Businesses looking to source high-quality 3-Chloropropyne from a reliable manufacturer in China will find NINGBO INNO PHARMCHEM CO.,LTD. to be a dependable partner, committed to excellence in product quality and customer service.