For research scientists and laboratory managers, access to high-quality specialty chemicals is fundamental to groundbreaking discoveries. 3-Chloropyridine (CAS 626-60-8) is a versatile organic compound that plays a significant role in various laboratory applications, particularly in organic synthesis and the development of novel materials. Understanding its properties and procurement channels is essential for efficient laboratory operations.

3-Chloropyridine is a heterocyclic aromatic organic compound belonging to the pyridine family, characterized by a chlorine atom substituted at the 3-position of the pyridine ring. Its physical form is typically a clear to yellow liquid, with a molecular formula of C5H4ClN and a molecular weight of approximately 113.54 g/mol. The compound's chemical structure offers reactive sites that are highly valuable for synthetic chemists exploring new molecular architectures.

Key Chemical Properties and Reactivity

The reactivity of 3-Chloropyridine stems from the electron-withdrawing nature of the chlorine atom and the inherent properties of the pyridine ring. It readily participates in a variety of reactions, including:

  • Nucleophilic Aromatic Substitution: The chlorine atom can be displaced by various nucleophiles, allowing for the introduction of different functional groups onto the pyridine ring.
  • Metal-Catalyzed Cross-Coupling Reactions: It can undergo Suzuki, Stille, or Buchwald-Hartwig couplings, forming new carbon-carbon or carbon-heteroatom bonds, which are vital for building complex organic molecules.
  • Derivatization: The pyridine nitrogen can be quaternized or oxidized, further expanding the synthetic utility of 3-Chloropyridine.

These reactions make it an ideal starting material for synthesizing a broad spectrum of compounds, from pharmaceutical intermediates to materials science precursors.

Applications in Research and Development

In academic and industrial research settings, 3-Chloropyridine is frequently employed as a key building block:

  • Drug Discovery: It is used to synthesize novel drug candidates and improve existing pharmaceutical molecules by incorporating the pyridine moiety for enhanced biological activity.
  • Agrochemical Research: It serves as an intermediate in the development of new pesticides and herbicides.
  • Materials Science: It can be utilized in the synthesis of functional materials, ligands for catalysis, or components for electronic devices.

Researchers often seek high-purity 3-Chloropyridine from reliable laboratory chemical suppliers to ensure the accuracy and reproducibility of their experiments.

Sourcing 3-Chloropyridine for Your Lab

When procuring 3-Chloropyridine, researchers should prioritize suppliers that offer comprehensive product information, including detailed specifications and safety data sheets (SDS). It is important to buy from manufacturers or distributors known for their quality control and reliability. Many reputable suppliers provide various packaging sizes to cater to different laboratory needs, from small research batches to larger pilot-scale quantities.

In conclusion, 3-Chloropyridine is a fundamental chemical tool for researchers engaged in synthesis and discovery. Understanding its properties and identifying trusted suppliers ensures access to this essential compound, thereby facilitating progress in various scientific disciplines. We offer high-purity 3-Chloropyridine for your laboratory needs, with a commitment to quality and customer satisfaction.