In the complex world of chemical synthesis, having access to well-characterized and consistently pure intermediates is fundamental to success. 4-Bromocatechol, identified by its CAS number 17345-77-6, is one such compound that plays a significant role in various industrial and research applications. Understanding its properties and how to source it effectively is crucial for chemists and procurement specialists alike.

Chemically known as 4-Bromocatechol or 4-Bromobenzene-1,2-diol, this substance is an aromatic organic compound. Its molecular formula is C6H5BrO2, with a molecular weight of approximately 189.01 g/mol. A key characteristic is its physical form: typically an off-white to light yellow crystalline powder. This solid state makes it convenient for handling and precise measurement in laboratory settings and during industrial processes. Its melting point is around 87°C, and its boiling point is approximately 280.5°C at standard atmospheric pressure, indicating good thermal stability under many reaction conditions.

The chemical reactivity of 4-Bromocatechol is attributed to its functional groups: two hydroxyl (-OH) groups and a bromine atom attached to a benzene ring. The hydroxyl groups make it a catechol derivative, imparting certain polar characteristics and enabling reactions such as etherification and esterification. The bromine atom serves as a reactive site for nucleophilic substitution and cross-coupling reactions, common in modern organic synthesis, including Suzuki, Heck, and Sonogashira couplings. This makes it an exceptionally versatile building block.

The primary application of 4-Bromocatechol is as an intermediate in organic synthesis. Its utility spans across several industries:

  • Pharmaceuticals: It is a critical precursor for synthesizing various drug molecules and active pharmaceutical ingredients (APIs). Its structure can be modified to create compounds with specific pharmacological activities.
  • Agrochemicals: In the agricultural sector, it is used to produce pesticides, herbicides, and other crop protection agents that are essential for modern farming.
  • Specialty Chemicals: It serves as a building block for a range of specialty chemicals, contributing to the development of new materials, dyes, and electronic components.
  • Research and Development: Academic and industrial R&D laboratories frequently utilize 4-Bromocatechol for exploring new synthetic methodologies and discovering novel compounds.

When considering the purchase of 4-Bromocatechol, sourcing from a reliable manufacturer is paramount. China has become a significant hub for chemical production, offering high-purity compounds at competitive prices. Buyers should look for suppliers that can guarantee a purity of ≥98.0% and provide a comprehensive Certificate of Analysis. Understanding the supplier's production capacity and their ability to ensure a stable supply chain is also important, especially for industrial-scale requirements. Obtaining a quote from a reputable supplier will allow you to assess pricing and availability, ensuring you can meet your project timelines and budget effectively.