Understanding 4-Methylpyridine N-Oxide: Properties, Handling, and Safety
When working with chemical compounds, a thorough understanding of their properties, appropriate handling procedures, and safety protocols is essential. 4-Methylpyridine N-Oxide, known by its CAS number 1003-67-4, is a chemical intermediate used in various industries, including pharmaceuticals and agrochemicals. This article provides an overview of its key characteristics, recommended handling practices, and crucial safety information to ensure its responsible use.
Chemical Properties and Identification:
4-Methylpyridine N-Oxide is an organic compound with the molecular formula C6H7NO and a molecular weight of approximately 109.13 g/mol. It is often described as a white to brown powder. Its synonyms include 4-Picoline N-oxide, 4-Methylpyridine 1-oxide, and gamma-Picoline N-oxide, among others. The compound is typically soluble in water and common organic solvents, which facilitates its use in various chemical reactions and formulations.
Handling and Storage:
Proper handling of 4-Methylpyridine N-Oxide is crucial to maintain its quality and ensure safety. It is often recommended to store the compound in a cool, dry, and well-ventilated area, away from incompatible materials. Some sources suggest storage at temperatures between 0-8°C to maintain its stability. When handling the powder, it is advisable to avoid dust formation and exposure. Wearing appropriate personal protective equipment (PPE), such as gloves, safety glasses, and lab coats, is standard practice. Minimizing dust generation and ensuring adequate ventilation in work areas are key to preventing inhalation exposure.
Safety Considerations:
While specific detailed safety data can be found in the Safety Data Sheet (SDS) provided by suppliers, general safety precautions for 4-Methylpyridine N-Oxide typically include avoiding contact with skin and eyes, and preventing inhalation of dust or vapors. Standard GHS hazard statements may include indications of skin irritation (H315), serious eye irritation (H319), and potential respiratory irritation (H335). Consequently, appropriate PPE and engineering controls, such as fume hoods, are important when working with this chemical. Users should always consult the most current SDS for comprehensive information on hazards, first-aid measures, fire-fighting procedures, and accidental release measures.
Applications and Usage:
4-Methylpyridine N-Oxide is primarily used as a chemical intermediate in the synthesis of pharmaceuticals and agrochemicals. Its utility as a mild oxidizing agent and a versatile building block in organic synthesis further expands its applications. When using it in synthesis, it's important to consider its compatibility with other reagents and reaction conditions. For instance, its role in pharmaceutical synthesis often involves multi-step processes where purity and precise reaction control are paramount. Similarly, in agrochemical production, its derivatives contribute to the efficacy of crop protection products.
Supplier Information:
Reliable sourcing of chemicals like 4-Methylpyridine N-Oxide is vital for research and manufacturing continuity. Companies like NINGBO INNO PHARMCHEM CO.,LTD. provide this compound, often with detailed product specifications and safety data. Buyers should always engage with reputable suppliers who can provide comprehensive documentation, including SDS and CoAs, to ensure product quality and adherence to safety standards.
In summary, understanding the properties and safety aspects of 4-Methylpyridine N-Oxide is fundamental for its effective and safe use. By adhering to proper handling, storage, and safety protocols, and by sourcing from trusted suppliers, researchers and manufacturers can confidently utilize this important chemical intermediate in their endeavors.
Chemical Properties and Identification:
4-Methylpyridine N-Oxide is an organic compound with the molecular formula C6H7NO and a molecular weight of approximately 109.13 g/mol. It is often described as a white to brown powder. Its synonyms include 4-Picoline N-oxide, 4-Methylpyridine 1-oxide, and gamma-Picoline N-oxide, among others. The compound is typically soluble in water and common organic solvents, which facilitates its use in various chemical reactions and formulations.
Handling and Storage:
Proper handling of 4-Methylpyridine N-Oxide is crucial to maintain its quality and ensure safety. It is often recommended to store the compound in a cool, dry, and well-ventilated area, away from incompatible materials. Some sources suggest storage at temperatures between 0-8°C to maintain its stability. When handling the powder, it is advisable to avoid dust formation and exposure. Wearing appropriate personal protective equipment (PPE), such as gloves, safety glasses, and lab coats, is standard practice. Minimizing dust generation and ensuring adequate ventilation in work areas are key to preventing inhalation exposure.
Safety Considerations:
While specific detailed safety data can be found in the Safety Data Sheet (SDS) provided by suppliers, general safety precautions for 4-Methylpyridine N-Oxide typically include avoiding contact with skin and eyes, and preventing inhalation of dust or vapors. Standard GHS hazard statements may include indications of skin irritation (H315), serious eye irritation (H319), and potential respiratory irritation (H335). Consequently, appropriate PPE and engineering controls, such as fume hoods, are important when working with this chemical. Users should always consult the most current SDS for comprehensive information on hazards, first-aid measures, fire-fighting procedures, and accidental release measures.
Applications and Usage:
4-Methylpyridine N-Oxide is primarily used as a chemical intermediate in the synthesis of pharmaceuticals and agrochemicals. Its utility as a mild oxidizing agent and a versatile building block in organic synthesis further expands its applications. When using it in synthesis, it's important to consider its compatibility with other reagents and reaction conditions. For instance, its role in pharmaceutical synthesis often involves multi-step processes where purity and precise reaction control are paramount. Similarly, in agrochemical production, its derivatives contribute to the efficacy of crop protection products.
Supplier Information:
Reliable sourcing of chemicals like 4-Methylpyridine N-Oxide is vital for research and manufacturing continuity. Companies like NINGBO INNO PHARMCHEM CO.,LTD. provide this compound, often with detailed product specifications and safety data. Buyers should always engage with reputable suppliers who can provide comprehensive documentation, including SDS and CoAs, to ensure product quality and adherence to safety standards.
In summary, understanding the properties and safety aspects of 4-Methylpyridine N-Oxide is fundamental for its effective and safe use. By adhering to proper handling, storage, and safety protocols, and by sourcing from trusted suppliers, researchers and manufacturers can confidently utilize this important chemical intermediate in their endeavors.
Perspectives & Insights
Molecule Vision 7
“Users should always consult the most current SDS for comprehensive information on hazards, first-aid measures, fire-fighting procedures, and accidental release measures.”
Alpha Origin 24
“Applications and Usage:4-Methylpyridine N-Oxide is primarily used as a chemical intermediate in the synthesis of pharmaceuticals and agrochemicals.”
Future Analyst X
“Its utility as a mild oxidizing agent and a versatile building block in organic synthesis further expands its applications.”